Fenpropathrin

Fenpropathrin
Identifiers

IUPAC name [Cyano-(3-phenoxyphenyl)methyl] 2,2,3,3-tetramethylcyclopropane-1-carboxylate
CAS Number	39515-41-8
PubChem CID	47326
ChemSpider	45352
UNII	87BH96P0MX
Chemical and physical data
Formula	C₂₂H₂₃NO₃
Molar mass	349.42292 g/mol
3D model (JSmol)	Interactive image
SMILES CC1(C(C1(C)C)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C
InChI InChI=InChI=1S/C22H23NO3/c1-21(2)19(22(21,3)4)20(24)26-18(14-23)15-9-8-12-17(13-15)25-16-10-6-5-7-11-16/h5-13,18-19H,1-4H3 Key:XQUXKZZNEFRCAW-UHFFFAOYSA-N

Fenpropathrin (brand names Danitol, Meothrin), or fenopropathrin, is a widely used pyrethroid insecticide in agriculture and household.^[1]^[2]^[3]^[4]

A person developed Parkinson's disease after six months of daily exposure to fenpropathrin, and animal tests subsequently revealed that the compound is a dopaminergic neurotoxin.^[4] It has thus been implicated as an environmental risk factor for Parkinson's disease.^[4]

References

↑ Hiroyasu Aizawa (2 December 2012). Metabolic Maps of Pesticides. Elsevier Science. pp. 185–. ISBN 978-0-323-15753-7.
↑ Mohamed B. Abou-Donia (15 July 1992). Neurotoxicology. CRC Press. pp. 462–. ISBN 978-1-4398-0542-8.
↑ Carl A. Johansen; Daniel F. Mayer (1990). Pollinator Protection: A Bee & Pesticide Handbook. Wicwas Press. ISBN 978-1-878075-00-0.
1 2 3 Xiong, Jing; Zhang, Xiaowei; Huang, Jinsha; Chen, Chunnuan; Chen, Zhenzhen; Liu, Ling; Zhang, Guoxin; Yang, Jiaolong; Zhang, Zhentao; Zhang, Zhaohui; Lin, Zhicheng; Xiong, Nian; Wang, Tao (2015). "Fenpropathrin, a Widely Used Pesticide, Causes Dopaminergic Degeneration". Molecular Neurobiology. 53 (2): 995–1008. ISSN 0893-7648. doi:10.1007/s12035-014-9057-2.

Pesticides
Pesticide types	Acaricide Bactericide Biocide Bioherbicide Biopesticide Fungicide Herbicide Insecticide Molluscicide Nematicide Piscicide Rodenticide
Related topics	Health effects Environmental effects Fumigation Agricultural spray adjuvant Biological pest control Gene silencing Green pest management Integrated pest management Maximum residue limit Non-pesticide management Persistent organic pollutant Pest control Application Drift Formulation Degradation Misuse Paradox of the pesticides Poisoning Research Residue Resistance Bee toxicity Restricted use Pesticide Action Network Silent Spring The Pesticide Question Toxicity Class
By country	Canada European Union New Zealand United States
Integrated Pest Management Index of pesticide articles Pesticide categories

Monoamine neurotoxins
Adrenergic	DSP-4 Oxidopamine (6-OHDA)
Dopaminergic	Fenpropathrin Methamphetamine MPP⁺ MPTP Norsalsolinol Oxidopamine (6-OHDA) Rotenone
Serotonergic	3-CA 4-CAB 5,7-DHT α-Me-DA (3,4-DHA) αET αMT DCA MDA MDMA PBA PCA PIA
See also: Receptor/signaling modulators • Adrenergics • Dopaminergics • Melatonergics • Serotonergics • Monoamine reuptake inhibitors • Monoamine releasing agents • Monoamine metabolism modulators

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Fenpropathrin

See also

References