Chlorphenoxamine

Chlorphenoxamine
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
Oral, topical
ATC code
Pharmacokinetic data
Bioavailability Well absorbed
Metabolism Likely hepatic
Excretion Renal
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
ECHA InfoCard 100.115.538
Chemical and physical data
Formula C18H22ClNO
Molar mass 303.826 g/mol
3D model (JSmol)
 NYesY (what is this?)  (verify)

Chlorphenoxamine (Phenoxene) is an antihistamine and anticholinergic used as an antipruritic[1] and antiparkinsonian[2] agent. It is an analog of diphenhydramine.[3]

References

  1. Bazex, A.; Dupre, A.; Christol, B. (1963). "Trial treatment of urticaria with chlorphenoxamine". Clinique (Paris, France). 58: 447–450. PMID 13967113.
  2. Uldall, P. R.; Walton, J. N.; Newell, D. J. (1961). "Chlorphenoxamine hydrochloride in parkinsonism. A controlled trial". British Medical Journal. 1 (5240): 1649–1652. PMC 1954253Freely accessible. PMID 13779077. doi:10.1136/bmj.1.5240.1649.
  3. H. Arnold, N. Brock, E. Kuhas, and D. Lorenz, Arzneimittel Forsch., 4, 189 (1954).


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