Acanthocystis turfacea chlorella virus 1

Acanthocystis turfacea chlorella virus 1
Virus classification
Group: Group I (dsDNA)
Family: Phycodnaviridae
Genus: Chlorovirus
Species

Chlorovirus ATCV-1

Acanthocystis turfacea chlorella virus 1 (ATCV-1), also called Chlorovirus ATCV-1 or Chlorella virus ATCV-1 is a species of giant double-stranded DNA virus in the Chlorovirus genus.

The host of ATCV-1 is Chlorella heliozoae; there is no evidence that ATCV-1 can infect other Chlorella species.

Human infection

DNA from ATCV-1 has been isolated from the mucous membranes of the noses of humans. In both humans and mice, the presence of ATCV-1 on the oropharyngeal mucosa was associated with lower scores in tests of cognitive and motor skills.[1][2] However, other investigators suggested that the Yolken et al results originated from low level laboratory contamination.[3]

References

  1. ↑ Yolken, R. H.; Jones-Brando, L.; Dunigan, D. D.; Kannan, G.; Dickerson, F.; Severance, E.; Sabunciyan, S.; Talbot, C. C.; Prandovszky, E.; Gurnon, J. R.; Agarkova, I. V.; Leister, F.; Gressitt, K. L.; Chen, O.; Deuber, B.; Ma, F.; Pletnikov, M. V.; Van Etten, J. L. (2014). "Chlorovirus ATCV-1 is part of the human oropharyngeal virome and is associated with changes in cognitive functions in humans and mice". Proc Natl Acad Sci U S A. 111: 16106–11. PMC 4234575 Freely accessible. PMID 25349393. doi:10.1073/pnas.1418895111.
  2. ↑ Elizabeth Pennisi (27 October 2014), "Algal virus found in humans, slows brain activity", Science
  3. ↑ Kjartansdóttir, Kristín Rós; Friis-Nielsen, Jens; Asplund, Maria; Mollerup, Sarah; Mourier, Tobias; Jensen, Randi Holm; Hansen, Thomas Arn; Rey-Iglesia, Alba; Richter, Stine Raith; Alquezar-Planas, David E.; Olsen, Pernille V. S.; Vinner, Lasse; Fridholm, Helena; Sicheritz-Pontén, Thomas; Nielsen, Lars Peter; Brunak, Søren; Willerslev, Eske; Izarzugaza, Jose M. G.; Hansen, Anders Johannes (2015). "Traces of ATCV-1 associated with laboratory component contamination". Proceedings of the National Academy of Sciences. 112 (9): E925–E926. ISSN 0027-8424. doi:10.1073/pnas.1423756112.
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