Catherine Dulac
| Catherine Dulac | |
|---|---|
 | |
| Born | 1963[1] |
| Alma mater | University of Paris |
| Academic advisors | Richard Axel |
| Known for | Mammalian pheromones |
| Notable awards | Richard Lounsbery Award |
Catherine Dulac is the Higgins Professor in Molecular and Cellular Biology at Harvard University. She is also an investigator at the Howard Hughes Medical Institute. She was born in 1963 in France. She came to the united states for her postdoctoral study in 1991. She is most notable for her research on the molecular biology of olfactory signaling in mammals, particularly including pheromones.[2] She developed a novel screening strategy based on screening cDNA libraries from single neurons and a new method of cloning genes from single neurons. As a postdoc, Dulac discovered the first family of mammalian pheromone receptors when working in Nobel laureate Richard Axel's laboratory at Columbia University.[3]
Biography
Dulac grew up in Montpellier, France, graduated from the École Normale Supérieure de la rue d'Ulm, Paris, and earned a Ph.D. in developmental biology from the University of Paris in 1991.[1] She worked with Nicole Le Douarin on developmental biology, and carried out her postdoc studies with Richard Axel at Columbia University where she identified the first genes encoding mammalian pheromone receptors.
Dulac joined the faculty of Harvard Molecular and Cell Biology in 1996,[4] She was promoted to associate professor in 2000 and full professor in 2001. She is currently an investigator at the Howard Hughes Medical Institute and was the Chair of Harvard's Department of Molecular and Cellular Biology[1] until 2013. She teaches three graduate level course including Molecular Basis of Behavior, Molecular and Cellular Biology of the Senses and Their Disorders, and Molecular and Developmental Biology Neurobiology.
Publications
Notable papers
- Kimchi T., Xu, J., and Dulac, C. "A Functional Circuit Underlying Male Sexual Behaviour in the Female Mouse Brain," Nature, v.448, pp. 1009–1014 (2007).
- Tietjen I, Rihel JM, Cao Y, Koentges G, Zakhary L, Dulac C. "Single-cell transcriptional analysis of neuronal progenitors.", Neuron, v.38, pp. 161–75 (2003).
- Pantages, E., and Dulac, C. "A New Family of Candidate Pheromone Receptors in Mammals," Neuron, v.28, pp. 835–845 (2000).
- Liman, E., Corey, D., and Dulac, C. "TRP2: A Candidate Transduction Channel for Mammalian Pheromone Sensory Signaling", PNAS, v.96, pp. 5791–5796 (1999).
- Belluscio, L., Koentges, G., Axel, R., and Dulac, C., "A Map of Pheromone Receptor Activation in the Mammalian Brain," Cell, v.97, pp. 209–220 (1999).
- Dulac C. and Axel R., "A Novel Family of Genes Encoding Putative Pheromone Receptors in Mammals," Cell, v.83, pp. 195–206 (1995).
Other
- Dulac, C. "Sex and the Single Splice," Cell, v.121, pp. 664–666 (2005).
- Dulac, C. and Grothe, B. "Editorial: Sensory Systems." Current Opinion in Neurobiology, v.14, pp. 403–406 (2004).
- Dulac, C. and Torello, A.T., Review, "Molecular Detection of Pheromone Signals in Mammals: From Genes to Behaviour." Nature Reviews Neuroscience, v. 4, pp. 1–13 (2003)
- Dulac, C. "The Physiology of Taste, Vintage 2000", Cell, v.100, pp. 607–610 (2000).
Awards and Honors
- 1998 Searle Scholar[1]
- 2004 Member, American Academy of Arts and Sciences[1][5]
- 2006 Richard Lounsbery Award[1]
- 2007 Member, French Academy of Sciences[1]
- 2015 Pradel Research Award by the National Academy of Sciences[1]
- 2017 Scolnick Prize by the McGovern Institute
References
- 1 2 3 4 5 6 7 8 . academie-sciences.fr
- ↑ Gitschier, J. (2011). "Vive La Différence: An Interview with Catherine Dulac". PLoS Genetics. 7 (6): e1002140. PMC 3121755
. PMID 21731502. doi:10.1371/journal.pgen.1002140. - ↑ "Catherine Dulac". Harvard University. Archived from the original on June 15, 2011. Retrieved 15 June 2011.
- ↑ "Harvard Portrait: Catherine Dulac", Harvard Magazine, Sept. – Oct. 2005.
- ↑ Hastings, J. W. (12 May 2004) "Catherine Dulac Elected to Membership in the American Academy of Arts and Sciences", Harvard University MCB News.
External links
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Wikimedia Commons has media related to Catherine Dulac. |
- Research Summary & Profile, Harvard University
- HHMI profile
- "Pheromones Control Gender Recognition in Mice", Jan. 31, 2002 (HHMI Research News)
- "Harvard Portrait: Catherine Dulac",
- "Making the Paper: Catherine Dulac", Nature, v.448 (Aug. 30, 2007).
- Catherine Dulac Seminars: "Sex and Smell: Molecular Biology of Pheromone Perception"
- Catherine Dulac Seminar: "The Molecular Biology of Smell"
- Catherine Dulac Seminar: "Gender Identification"
- Catherine Dulac Seminar: "Hard Wired Behavior"
- Catherine Dulac Seminar: "Synesthesia"