Carbonyl cyanide-''p''-trifluoromethoxyphenylhydrazone

Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone^[1]
Names

IUPAC name 2-[[4-(trifluoromethoxy)phenyl]hydrazinylidene]propanedinitrile
Identifiers
CAS Number	370-86-5^Y
3D model (JSmol)	Interactive image Interactive image
ChEBI	CHEBI:75458^N
ChemSpider	3213^Y
ECHA InfoCard	100.006.119
MeSH	FCCP
PubChem CID	3330
InChI InChI=1S/C10H5F3N4O/c11-10(12,13)18-9-3-1-7(2-4-9)16-17-8(5-14)6-15/h1-4,16H^Y Key: BMZRVOVNUMQTIN-UHFFFAOYSA-N^Y InChI=1/C10H5F3N4O/c11-10(12,13)18-9-3-1-7(2-4-9)16-17-8(5-14)6-15/h1-4,16H Key: BMZRVOVNUMQTIN-UHFFFAOYAT
SMILES C1=CC(=CC=C1NN=C(C#N)C#N)OC(F)(F)F FC(F)(F)Oc1ccc(cc1)N/N=C(\C#N)C#N
Properties
Chemical formula	C₁₀H₅F₃N₄O
Molar mass	254.16811 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

Carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone (FCCP) is an ionophore that is a mobile ion carrier. It is referred to as an uncoupling agent because it disrupts ATP synthesis by transporting hydrogen ions through a cell membrane before they can be used to provide the energy for oxidative phosphorylation.^[2] It is a nitrile and hydrazone. FCCP was first described in 1962 by Heytler.^[3]

References

↑ FCCP - Compound Summary, PubChem.
↑ MeSH Descriptor Data, MeSH.
↑ Heytler, P G (1962). "A new class of uncoupling agents — Carbonyl cyanide phenylhydrazones". Biochemical and Biophysical Research Communications. 7 (4): 272–275. doi:10.1016/0006-291X(62)90189-4.

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