Capillin
 | |
| Names | |
|---|---|
| IUPAC name
1-phenylhexa-2,4-diyn-1-one | |
| Other names
Capillin | |
| Identifiers | |
| 3D model (JSmol) |
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| ChemSpider | |
| PubChem CID |
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| Properties | |
| C12H8O | |
| Molar mass | 168.20 g·mol−1 |
| Melting point | 82–83 °C |
| 0.0177 mg/mL | |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Capillin is a naturally occurring organic compound with the chemical formula C
12H
8O. The structure contains acetophenone and a polyyne portions, conjugated together as an ynone.
Chemical taxonomy
Capillin is found in the essential oil of a number of Artemisia species, including Artemisia monosperma and Artemisia dracunculus (tarragon).[1] The substance was initially isolated from Artemisia capillaris in 1956.[2]
Applications
Capillin is a biologically active substance. It has strong antifungal activity, and it is possibly antitumoral. Capillin exhibits cytotoxic activity and could cause apoptosis of certain human tumor cells.[3]
References
- ↑ "Showing metabocard for Capillin (HMDB32867)". Human Metabolome Database. hmdb.ca. Retrieved 17 May 2017.
- ↑ Nash, B. W.; Thomas, D. A.; Warburton, W. K.; Williams, Thelma D. (1965). "535. The preparation of capillin and some related compounds, and of some substituted pent-4-en-2-yn-1-ones". J. Chem. Soc.: 2983-2988. doi:10.1039/JR9650002983.
- ↑ WHELAN, L.C.; RYAN, M.F. (2004). "Effects of the Polyacetylene Capillin on Human Tumour Cell Lines". Anticancer Research (24): 2281-2286.
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