CSN3 (gene)

CSN3

Identifiers

CSN3, CSN10, CSNK, KCA, CNS10, casein kappa

External IDs

MGI: 107461 HomoloGene: 3818 GeneCards: CSN3

Gene ontology
Molecular function	• protein binding
Cellular component	• extracellular region • extracellular space
Biological process	• protein stabilization • lactation • transmembrane transport
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


1448


12994


ENSG00000171209


ENSMUSG00000001622


P07498


P06796

RefSeq (mRNA)


NM_005212


NM_007786

RefSeq (protein)


NP_005203


NP_031812

Location (UCSC)

Chr 4: 70.24 – 70.25 Mb

Chr 5: 87.93 – 87.93 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

Kappa-casein is a protein that in humans is encoded by the CSN3 gene.^[3]^[4]^[5]

Interactions

CSN3 (gene) has been shown to interact with EIF3S6.^[6]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Edlund A, Johansson T, Leidvik B, Hansson L (Nov 1996). "Structure of the human kappa-casein gene". Gene. 174 (1): 65–9. PMID 8863730. doi:10.1016/0378-1119(96)00351-4.
↑ Fujiwara Y, Miwa M, Nogami M, Okumura K, Nobori T, Suzuki T, Ueda M (Mar 1997). "Genomic organization and chromosomal localization of the human casein gene family". Hum Genet. 99 (3): 368–73. PMID 9050925. doi:10.1007/s004390050374.
↑ "Entrez Gene: CSN3 casein kappa".
↑ Hoareau Alves, Karine; Bochard Valérie; Réty Stéphane; Jalinot Pierre (Sep 2002). "Association of the mammalian proto-oncoprotein Int-6 with the three protein complexes eIF3, COP9 signalosome and 26S proteasome". FEBS Lett. Netherlands. 527 (1-3): 15–21. ISSN 0014-5793. PMID 12220626. doi:10.1016/S0014-5793(02)03147-2.

External links

Human CSN3 genome location and CSN3 gene details page in the UCSC Genome Browser.

Further reading

Bergström S, Hansson L, Hernell O, et al. (1993). "Cloning and sequencing of human kappa-casein cDNA.". DNA Seq. 3 (4): 245–6. PMID 1296818. doi:10.3109/10425179209034024.
Brignon G, Chtourou A, Ribadeau-Dumas B (1985). "Preparation and amino acid sequence of human kappa-casein.". FEBS Lett. 188 (1): 48–54. PMID 4018271. doi:10.1016/0014-5793(85)80872-3.
Fiat AM, Jollès J, Aubert JP, et al. (1981). "Localisation and importance of the sugar part of human casein.". Eur. J. Biochem. 111 (2): 333–9. PMID 7460900. doi:10.1111/j.1432-1033.1980.tb04946.x.
Plowman JE, Creamer LK, Liddell MJ, Cross JJ (1999). "Structural features of a peptide corresponding to human kappa-casein residues 84-101 by 1H-nuclear magnetic resonance spectroscopy.". J. Dairy Res. 66 (1): 53–63. PMID 10191473. doi:10.1017/S0022029998003318.
Harrington JJ, Sherf B, Rundlett S, et al. (2001). "Creation of genome-wide protein expression libraries using random activation of gene expression.". Nat. Biotechnol. 19 (5): 440–5. PMID 11329013. doi:10.1038/88107.
Benítez MJ, Cochet C, Jiménez JS (2002). "A surface plasmon resonance study of the interactions between the component subunits of protein kinase CK2 and two protein substrates, casein and calmodulin.". Mol. Cell. Biochem. 227 (1-2): 31–6. PMID 11827172. doi:10.1023/A:1013140220121.
Sood SM, Slatter CW (2003). "Suspension of the calcium-sensitive human beta-caseins by human kappa-casein.". J. Dairy Sci. 85 (6): 1353–6. PMID 12146463. doi:10.3168/jds.S0022-0302(02)74200-8.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Kim YJ, Park S, Oh YK, et al. (2005). "Purification and characterization of human caseinomacropeptide produced by a recombinant Saccharomyces cerevisiae.". Protein Expr. Purif. 41 (2): 441–6. PMID 15866733. doi:10.1016/j.pep.2005.02.021.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature. 437 (7062): 1173–8. PMID 16189514. doi:10.1038/nature04209.

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