CNTROB

CNTROB
Identifiers
AliasesCNTROB, LIP8, PP1221, centrobin, centriole duplication and spindle assembly protein
External IDsMGI: 2443290 HomoloGene: 14205 GeneCards: CNTROB
Orthologs
SpeciesHumanMouse
Entrez

116840

216846

Ensembl

ENSG00000170037

ENSMUSG00000032782

UniProt

Q8N137

Q8CB62

RefSeq (mRNA)

NM_001037144
NM_053051
NM_001330124

NM_172560

RefSeq (protein)

NP_766148

Location (UCSC)Chr 17: 7.93 – 7.95 MbChr 11: 69.3 – 69.32 Mb
PubMed search[1][2]
Wikidata
View/Edit HumanView/Edit Mouse

Centrobin is a protein that in humans is encoded by the CNTROB gene.[3] It is a centriole-associated protein that asymmetrically localizes to the daughter centriole, and is required for centriole duplication and cytokinesis.[4]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Tchernev, V. T.; Mansfield, T. A.; Giot, L.; Kumar, A. M.; Nandabalan, K.; Li, Y.; Mishra, V. S.; Detter, J. C.; Rothberg, J. M.; Wallace, M. R.; Southwick, F. S.; Kingsmore, S. F. (2002). "The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins". Molecular medicine (Cambridge, Mass.). 8 (1): 56–64. PMC 2039936Freely accessible. PMID 11984006.
  4. Zou, C.; Li, J.; Bai, Y.; Gunning, W.; Wazer, D.; Band, V.; Gao, Q. (2005). "Centrobin: a novel daughter centriole-associated protein that is required for centriole duplication". Journal of Cell Biology. 171 (3): 437–445. PMC 2171251Freely accessible. PMID 16275750. doi:10.1083/jcb.200506185.

Further reading


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