CFHR3

CFHR3

Identifiers

CFHR3, CFHL3, DOWN16, FHR-3, FHR3, HLF4, complement factor H related 3

External IDs

HomoloGene: 137347 GeneCards: CFHR3

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


10878


n/a


ENSG00000116785


n/a


Q02985


n/a

RefSeq (mRNA)


NM_001166624 NM_021023


n/a

RefSeq (protein)


NP_001160096 NP_066303


n/a

Location (UCSC)

Chr 1: 196.77 – 196.8 Mb

n/a

PubMed search

^[1]

n/a

View/Edit Human

Complement factor H-related protein 3 is a protein that in humans is encoded by the CFHR3 gene.^[2]^[3]^[4]

References

↑ "Human PubMed Reference:".
↑ Skerka C, Kuhn S, Gunther K, Lingelbach K, Zipfel PF (Mar 1993). "A novel short consensus repeat-containing molecule is related to human complement factor H". J Biol Chem. 268 (4): 2904–8. PMID 8428964.
↑ Diaz-Guillen MA, Rodriguez de Cordoba S, Heine-Suner D (Jul 1999). "A radiation hybrid map of complement factor H and factor H-related genes". Immunogenetics. 49 (6): 549–52. PMID 10380701. doi:10.1007/s002510050534.
↑ "Entrez Gene: CFHR3 complement factor H-related 3".

Further reading

Zipfel PF, Skerka C (1994). "Complement factor H and related proteins: an expanding family of complement-regulatory proteins?". Immunol. Today. 15 (3): 121–6. PMID 8172644. doi:10.1016/0167-5699(94)90155-4.
Hellwage J, Jokiranta TS, Koistinen V, et al. (2000). "Functional properties of complement factor H-related proteins FHR-3 and FHR-4: binding to the C3d region of C3b and differential regulation by heparin.". FEBS Lett. 462 (3): 345–52. PMID 10622723. doi:10.1016/S0014-5793(99)01554-9.
Male DA, Ormsby RJ, Ranganathan S, et al. (2000). "Complement factor H: sequence analysis of 221 kb of human genomic DNA containing the entire fH, fHR-1 and fHR-3 genes.". Mol. Immunol. 37 (1-2): 41–52. PMID 10781834. doi:10.1016/S0161-5890(00)00024-9.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature. 441 (7091): 315–21. PMID 16710414. doi:10.1038/nature04727.
Zipfel PF, Edey M, Heinen S, et al. (2007). "Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome.". PLoS Genet. 3 (3): e41. PMC 1828695 . PMID 17367211. doi:10.1371/journal.pgen.0030041.

External links

GeneReviews/NCBI/NIH/UW entry on Atypical Hemolytic-Uremic Syndrome
OMIM entries on Atypical Hemolytic-Uremic Syndrome
Human CFHR3 genome location and CFHR3 gene details page in the UCSC Genome Browser.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.