CFHR1
CFHR1 |
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Identifiers |
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Aliases | CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2, complement factor H related 1 |
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External IDs | MGI: 2138169 HomoloGene: 55632 GeneCards: CFHR1 |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 1: 196.82 – 196.83 Mb | Chr 1: 139.55 – 139.56 Mb |
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PubMed search | [1] | [2] |
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Wikidata |
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Complement factor H-related protein 1 is a protein that in humans is encoded by the CFHR1 gene.[3][4][5]
References
Further reading
- Zipfel PF, Skerka C (1994). "Complement factor H and related proteins: an expanding family of complement-regulatory proteins?". Immunol. Today. 15 (3): 121–6. PMID 8172644. doi:10.1016/0167-5699(94)90155-4.
- Zipfel PF, Jokiranta TS, Hellwage J, et al. (1999). "The factor H protein family.". Immunopharmacology. 42 (1-3): 53–60. PMID 10408366. doi:10.1016/S0162-3109(99)00015-6.
- Timmann C, Leippe M, Horstmann RD (1991). "Two major serum components antigenically related to complement factor H are different glycosylation forms of a single protein with no factor H-like complement regulatory functions.". J. Immunol. 146 (4): 1265–70. PMID 1825108.
- Park CT, Wright SD (1996). "Plasma lipopolysaccharide-binding protein is found associated with a particle containing apolipoprotein A-I, phospholipid, and factor H-related proteins.". J. Biol. Chem. 271 (30): 18054–60. PMID 8663389. doi:10.1074/jbc.271.30.18054.
- Díaz-Guillén MA, Rodríguez de Córdoba S, Heine-Suñer D (1999). "A radiation hybrid map of complement factor H and factor H-related genes.". Immunogenetics. 49 (6): 549–52. PMID 10380701. doi:10.1007/s002510050534.
- Male DA, Ormsby RJ, Ranganathan S, et al. (2000). "Complement factor H: sequence analysis of 221 kb of human genomic DNA containing the entire fH, fHR-1 and fHR-3 genes.". Mol. Immunol. 37 (1-2): 41–52. PMID 10781834. doi:10.1016/S0161-5890(00)00024-9.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
- Pérez-Caballero D, García-Laorden I, Cortés G, et al. (2005). "Interaction between complement regulators and Streptococcus pyogenes: binding of C4b-binding protein and factor H/factor H-like protein 1 to M18 strains involves two different cell surface molecules.". J. Immunol. 173 (11): 6899–904. PMID 15557185. doi:10.4049/jimmunol.173.11.6899.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature. 437 (7062): 1173–8. PMID 16189514. doi:10.1038/nature04209.
- McDowell JV, Lankford J, Stamm L, et al. (2005). "Demonstration of factor H-like protein 1 binding to Treponema denticola, a pathogen associated with periodontal disease in humans.". Infect. Immun. 73 (11): 7126–32. PMC 1273895 . PMID 16239506. doi:10.1128/IAI.73.11.7126-7132.2005.
- Liu T, Qian WJ, Gritsenko MA, et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.". J. Proteome Res. 4 (6): 2070–80. PMC 1850943 . PMID 16335952. doi:10.1021/pr0502065.
- Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature. 441 (7091): 315–21. PMID 16710414. doi:10.1038/nature04727.
- Zipfel PF, Edey M, Heinen S, et al. (2007). "Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome.". PLoS Genet. 3 (3): e41. PMC 1828695 . PMID 17367211. doi:10.1371/journal.pgen.0030041.
- Haupt K, Kraiczy P, Wallich R, et al. (2007). "Binding of human factor H-related protein 1 to serum-resistant Borrelia burgdorferi is mediated by borrelial complement regulator-acquiring surface proteins.". J. Infect. Dis. 196 (1): 124–33. PMID 17538892. doi:10.1086/518509.
PDB gallery |
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| 2bzm: SOLUTION STRUCTURE OF THE PRIMARY HOST RECOGNITION REGION OF COMPLEMENT FACTOR H |
| 2g7i: Structure of Human Complement Factor H Carboxyl Terminal Domains 19-20: a Basis for Atypical Hemolytic Uremic Syndrome |
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External links