CENPI
| CENPI | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||||||
| Aliases | CENPI, CENP-I, FSHPRH1, LRPR1, Mis6, centromere protein I | ||||||||||||||||
| External IDs | MGI: 2147897 HomoloGene: 4899 GeneCards: CENPI | ||||||||||||||||
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| RNA expression pattern | |||||||||||||||||
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| More reference expression data | |||||||||||||||||
| Orthologs | |||||||||||||||||
| Species | Human | Mouse | |||||||||||||||
| Entrez | |||||||||||||||||
| Ensembl | |||||||||||||||||
| UniProt | |||||||||||||||||
| RefSeq (mRNA) | |||||||||||||||||
| RefSeq (protein) | |||||||||||||||||
| Location (UCSC) | Chr X: 101.1 – 101.16 Mb | Chr X: 134.31 – 134.36 Mb | |||||||||||||||
| PubMed search | [1] | [2] | |||||||||||||||
| Wikidata | |||||||||||||||||
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Centromere protein I is a protein that in humans is encoded by the CENPI gene.[3][4]
The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. This gene is also a potential candidate for human X-linked disorders of gonadal development and gametogenesis.[4]
References
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ Okada M, Cheeseman IM, Hori T, Okawa K, McLeod IX, Yates JR 3rd, Desai A, Fukagawa T (May 2006). "The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres". Nat Cell Biol. 8 (5): 446–57. PMID 16622420. doi:10.1038/ncb1396.
- 1 2 "Entrez Gene: CENPI centromere protein I".
External links
- Human CENPI genome location and CENPI gene details page in the UCSC Genome Browser.
Further reading
- Izuta H, Ikeno M, Suzuki N, et al. (2006). "Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells.". Genes Cells. 11 (6): 673–84. PMID 16716197. doi:10.1111/j.1365-2443.2006.00969.x.
- Foltz DR, Jansen LE, Black BE, et al. (2006). "The human CENP-A centromeric nucleosome-associated complex.". Nat. Cell Biol. 8 (5): 458–69. PMID 16622419. doi:10.1038/ncb1397.
- Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle.". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. PMC 1459365
. PMID 16565220. doi:10.1073/pnas.0507066103. - Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome.". Nature. 434 (7031): 325–37. PMC 2665286 . PMID 15772651. doi:10.1038/nature03440.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
- Obuse C, Yang H, Nozaki N, et al. (2004). "Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase.". Genes Cells. 9 (2): 105–20. PMID 15009096. doi:10.1111/j.1365-2443.2004.00705.x.
- Liu ST, Hittle JC, Jablonski SA, et al. (2003). "Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis.". Nat. Cell Biol. 5 (4): 341–5. PMID 12640463. doi:10.1038/ncb953.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
- Roberts RG, Kendall E, Vetrie D, Bobrow M (1997). "Sequence and chromosomal location of a human homologue of LRPR1, an FSH primary response gene.". Genomics. 37 (1): 122–4. PMID 8921378. doi:10.1006/geno.1996.0528.
- Slegtenhorst-Eegdeman KE, Post M, Baarends WM, et al. (1995). "Regulation of gene expression in Sertoli cells by follicle-stimulating hormone (FSH): cloning and characterization of LRPR1, a primary response gene encoding a leucine-rich protein.". Mol. Cell. Endocrinol. 108 (1-2): 115–24. PMID 7758824. doi:10.1016/0303-7207(94)03468-9.
- Adams MD, Dubnick M, Kerlavage AR, et al. (1992). "Sequence identification of 2,375 human brain genes.". Nature. 355 (6361): 632–4. PMID 1538749. doi:10.1038/355632a0.
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