CD5L

CD5L

Identifiers

CD5L, AIM, API6, PRO229, SP-ALPHA, Spalpha, CT-2, hAIM, CD5 molecule like

External IDs

MGI: 1334419 HomoloGene: 55936 GeneCards: CD5L

Gene ontology
Molecular function	• scavenger receptor activity
Cellular component	• cytoplasm • extracellular region • extracellular exosome • blood microparticle • membrane • extracellular space
Biological process	• cellular defense response • inflammatory response • receptor-mediated endocytosis • immune system process • apoptotic process
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


922


11801


ENSG00000073754


ENSMUSG00000015854


O43866


Q9QWK4

RefSeq (mRNA)


NM_005894 NM_001347698


NM_009690

RefSeq (protein)


NP_001334627 NP_005885


NP_033820

Location (UCSC)

Chr 1: 157.83 – 157.9 Mb

Chr 3: 87.36 – 87.37 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

CD5 antigen-like is a protein that in humans is encoded by the CD5L gene.^[3]^[4]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Gebe JA, Kiener PA, Ring HZ, Li X, Francke U, Aruffo A (Apr 1997). "Molecular cloning, mapping to human chromosome 1 q21-q23, and cell binding characteristics of Spalpha, a new member of the scavenger receptor cysteine-rich (SRCR) family of proteins". J Biol Chem. 272 (10): 6151–8. PMID 9045627. doi:10.1074/jbc.272.10.6151.
↑ "Entrez Gene: CD5L CD5 molecule-like".

External links

Human CD5L genome location and CD5L gene details page in the UCSC Genome Browser.

Further reading

Tissot JD, Schifferli JA, Hochstrasser DF, et al. (1994). "Two-dimensional polyacrylamide gel electrophoresis analysis of cryoglobulins and identification of an IgM-associated peptide". J. Immunol. Methods. 173 (1): 63–75. PMID 8034987. doi:10.1016/0022-1759(94)90284-4.
Tissot JD, Sanchez JC, Vuadens F, et al. (2002). "IgM are associated to Sp alpha (CD5 antigen-like)". Electrophoresis. 23 (7–8): 1203–6. PMID 11981870. doi:10.1002/1522-2683(200204)23:7/8<1203::AID-ELPS1203>3.0.CO;2-1.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. PMC 403697 . PMID 12975309. doi:10.1101/gr.1293003.
Anderson NL, Polanski M, Pieper R, et al. (2004). "The human plasma proteome: a nonredundant list developed by combination of four separate sources". Mol. Cell Proteomics. 3 (4): 311–26. PMID 14718574. doi:10.1074/mcp.M300127-MCP200.
Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. PMC 2286551 . PMID 15340161. doi:10.1110/ps.04682504.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Sarrias MR, Roselló S, Sánchez-Barbero F, et al. (2005). "A role for human Sp alpha as a pattern recognition receptor". J. Biol. Chem. 280 (42): 35391–8. PMID 16030018. doi:10.1074/jbc.M505042200.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. PMID 16710414. doi:10.1038/nature04727.

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