CC-preferring endodeoxyribonuclease

Identifiers

Databases

PDB structures

CC-preferring endodeoxyribonuclease (EC 3.1.21.6, Streptomyces glaucescens exocytoplasmic dodeoxyribonuclease) is an enzyme.^[1]^[2] This enzyme catalyses the following chemical reaction

endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC

This enzyme has preference for CC sites in double-stranded circular and linear DNA.

References

↑ Xia YN, Morgan R, Schildkraut I, Van Etten JL (1988). "A site-specific single-strand endonuclease activity induced by NYs-1 virus-infection of a Chlorella-like green-alga". Nucleic Acids Res. 16 (20): 9477–9487. PMC 338757 . PMID 3186439. doi:10.1093/nar/16.20.9477.
↑ Aparicio JF, Freije JM, Lopez-Otin C, Cal S, Sanchez J (1992). "A Streptomyces glaucescens endodeoxyribonuclease which shows a strong preference for CC dinucleotide". Eur. J. Biochem. 205 (2): 695–699. PMID 1533367. doi:10.1111/j.1432-1033.1992.tb16831.x.

3.1.1: Carboxylic
ester hydrolases

Exodeoxyribonuclease	RecBCD
Exoribonuclease	Oligonucleotidase

Endodeoxyribonuclease	Deoxyribonuclease I Deoxyribonuclease II Deoxyribonuclease IV Restriction enzyme UvrABC endonuclease
Endoribonuclease	RNase III RNase H 1 2A 2B 2C RNase P RNase A 1 2 3 4/5 RNase T1 RNA-induced silencing complex
either deoxy- or ribo-	Aspergillus nuclease S1 Micrococcal nuclease

Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list)

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