Bugula neritina

Bugula neritina
The nudibranch Diaphorodoris papillata Portmann & Sandmeier, 1960 feeding on Bugula neritina (Linnaeus, 1758)
Scientific classification
Kingdom: Animalia
Phylum: Bryozoa
Class: Gymnolaemata
Order: Cheilostomata
Family: Bugulidae
Genus: Bugula
Species: B. neritina
Binomial name
Bugula neritina
(Linnaeus, 1758)[1]
Synonyms[2]

Sertularia neritina Linnaeus, 1758 (basionym)

Bugula neritina (commonly known as brown bryozoan or common bugula) is a cryptic species complex of sessile marine animal in the Bugula genus. [2]

It is invasive with a cosmopolitan distribution.[1]

Bugula neritina is of interest from a drug discovery perspective because it produces the bryostatins, a group of around twenty bioactive natural products. The bryostatins are under investigation as possible therapies for cancer[3][4] and Alzheimer's disease.[4][5]

Bugula neritina is also of interest in materials science, where it is used as a model organism in biofouling studies.[6]

References

  1. 1 2 "Bugula neritina (brown bryozoan)". CABI (organisation). 3 May 2013. Retrieved 14 March 2015.
  2. 1 2 Gordon, D. (2015). Bugula neritina (Linnaeus, 1758). In: Bock, P.; Gordon, D. (2015) World List of Bryozoa. Accessed through: World Register of Marine Species at http://www.marinespecies.org/aphia.php?p=taxdetails&id=111158 on 2015-09-02
  3. ↑ Singh R, Sharma M, Joshi P, Rawat DS (2008). "Clinical status of anti-cancer agents derived from marine sources". Anticancer Agents Med Chem. 8 (6): 603–617. PMID 18690825. doi:10.2174/187152008785133074.
  4. 1 2 Ruan BF, Zhu HL (2012). "The chemistry and biology of the bryostatins: potential PKC inhibitors in clinical development". Curr Med Chem. 19 (16): 2652–64. PMID 22506770. doi:10.2174/092986712800493020.
  5. ↑ "Bryostatin – Phase II clinical testing of a non-toxic PKC activator". Blanchette Rockefeller Neurosciences Institute (West Virginia University). Retrieved 14 March 2015.
  6. ↑ Yua X, Yana Y, Gua JD (2007). "Attachment of the biofouling bryozoan Bugula neritina larvae affected by inorganic and organic chemical cues". Int Biodeterior Biodegradation. 60 (2): 81–89. doi:10.1016/j.ibiod.2006.12.003.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.