Bromazine
Not to be confused with Promazine.
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| Clinical data | |
|---|---|
| MedlinePlus | a682065 |
| Routes of administration | Oral |
| ATC code | |
| Pharmacokinetic data | |
| Bioavailability | High |
| Protein binding | 96% |
| Metabolism | Mostly hepatic (CYP-mediated), also renal |
| Biological half-life | 1 to 4 hours |
| Identifiers | |
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| CAS Number | |
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| IUPHAR/BPS | |
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| ChEBI | |
| ChEMBL | |
| ECHA InfoCard | 100.003.854 |
| Chemical and physical data | |
| Formula | C17H20BrNO |
| Molar mass | 334.251 g/mol |
| 3D model (JSmol) | |
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Bromazine (trade names Ambrodyl, Ambrodil and others), also known as bromodiphenhydramine, is an antihistamine and anticholinergic.[1] It is a halogenated form of diphenhydramine and in many respects is somewhat stronger than the parent compound. The other three halogenated diphenhydramine derivatives are used in research and chlorodiphenhydramine is also marketed with iododiphenhydramine being a much less common pharmaceutical.
References
| Aminoalkyl ethers |
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| Substituted alkylamines | |
| Substituted ethylenediamines |
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| Phenothiazine derivatives | |
| Piperazine derivatives | |
| Others for systemic use |
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| For topical use | |
| H1 |
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| H2 |
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| H3 |
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| H4 |
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See also: Receptor/signaling modulators • Monoamine metabolism modulators • Monoamine reuptake and release modulators | |
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