Betaine reductase
Betaine reductase | |||||||||
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Identifiers | |||||||||
EC number | 1.21.4.4 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Betaine reductase (EC 1.21.4.4) is an enzyme that catalyzes the chemical reaction
- acetyl phosphate + trimethylamine + thioredoxin disulfide N,N,N-trimethylglycine + phosphate + thioredoxin
The 3 substrates of this enzyme are acetyl phosphate, trimethylamine, and thioredoxin disulfide, whereas its 3 products are N,N,N-trimethylglycine, phosphate, and thioredoxin.
This enzyme belongs to the family of oxidoreductases, specifically those acting on X-H and Y-H to form an X-Y bond with a disulfide as acceptor. The systematic name of this enzyme class is acetyl-phosphate trimethylamine:thioredoxin disulfide oxidoreductase (N,N,N-trimethylglycine-forming).
References
- Andreesen JR; Sonntag, D; Grimm, R; Pich, A; Eckerskorn, C; Söhling, B; Andreesen, JR (1999). "Substrate-specific selenoprotein B of glycine reductase from Eubacterium acidaminophilum. Biochemical and molecular analysis". Eur. J. Biochem. 260 (1): 38–49. PMID 10091582. doi:10.1046/j.1432-1327.1999.00107.x.
- Bednarski B, Andreesen JR, Pich A (2001). "In vitro processing of the proproteins GrdE of protein B of glycine reductase and PrdA of D-proline reductase from Clostridium sticklandii: formation of a pyruvoyl group from a cysteine residue". Eur. J. Biochem. 268 (12): 3538–44. PMID 11422384. doi:10.1046/j.1432-1327.2001.02257.x.
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