Benzamidine

Benzamidine
Names
IUPAC name
Benzenecarboximidamide
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.009.589
KEGG
Properties
C7H8N2
Molar mass 120.15 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Benzamidine is a reversible competitive inhibitor of trypsin, trypsin-like enzymes and serine proteases.

It is often used as a ligand in protein crystallography to prevent proteases from degrading a protein of interest; the triangular diamine group at the bottom gives it a very obvious 'stick-man' shape which shows up in difference density maps. The benzamidine moiety is also found in some pharmaceuticals, like dabigatran.


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