Bridging integrator 3

BIN3
Identifiers
Aliases	BIN3, bridging integrator 3
External IDs	MGI: 1929883 HomoloGene: 5472 GeneCards: BIN3
Gene ontology Molecular function • cytoskeletal adaptor activity • protein binding Cellular component • cytoplasm • cytoskeleton • actin filament Biological process • regulation of lamellipodium assembly • unidimensional cell growth • protein localization • barrier septum assembly • cell cycle • myoblast migration involved in skeletal muscle regeneration • cytokinesis • skeletal muscle fiber development • skeletal muscle tissue regeneration • actin filament organization • cell division Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	55909	57784
Ensembl	ENSG00000147439	ENSMUSG00000022089
UniProt	Q9NQY0	Q9JI08
RefSeq (mRNA)	NM_018688	NM_021328
RefSeq (protein)	NP_061158	NP_067303
Location (UCSC)	Chr 8: 22.62 – 22.67 Mb	Chr 14: 70.1 – 70.14 Mb
PubMed search	[1]	[2]
Wikidata
View/Edit Human View/Edit Mouse

Bridging integrator 3 is a protein that in humans is encoded by the BIN3 gene.^[3][4]

Function

The product of this gene is a member of the BAR domain protein family. The encoded protein is composed solely of a BAR domain which is predicted to form coiled coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes.^[4]

References

External links

• Human BIN3 genome location and BIN3 gene details page in the UCSC Genome Browser.

Further reading