BAZ2A

BAZ2A

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
4LZ2, 4Q6F, 4QBM, 4QF2, 5AGQ

Identifiers

BAZ2A, TIP5, WALp3, bromodomain adjacent to zinc finger domain 2A

External IDs

MGI: 2151152 HomoloGene: 8393 GeneCards: BAZ2A

Gene ontology
Molecular function	• DNA binding • RNA polymerase I CORE element sequence-specific DNA binding • histone binding • metal ion binding • protein binding • ligand-dependent nuclear receptor binding • lysine-acetylated histone binding • RNA binding
Cellular component	• rDNA heterochromatin • chromatin silencing complex • nucleolus • nucleus • cytosol • nuclear speck
Biological process	• chromatin remodeling • regulation of transcription, DNA-templated • transcription, DNA-templated • DNA methylation • chromatin silencing at rDNA • histone deacetylation • covalent chromatin modification
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


11176


116848


ENSG00000076108


ENSMUSG00000040054


Q9UIF9


Q91YE5

RefSeq (mRNA)


NM_001300905 NM_013449 NM_001351156


NM_054078

RefSeq (protein)


NP_001287834 NP_038477 NP_001338085


n/a

Location (UCSC)

Chr 12: 56.6 – 56.64 Mb

Chr 10: 128.09 – 128.13 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

Bromodomain adjacent to zinc finger domain protein 2A is a protein that in humans is encoded by the BAZ2A gene.^[3]^[4]^[5]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Jones MH, Hamana N, Nezu Ji, Shimane M (Jan 2000). "A novel family of bromodomain genes". Genomics. 63 (1): 40–5. PMID 10662543. doi:10.1006/geno.1999.6071.
↑ Strohner R, Nemeth A, Jansa P, Hofmann-Rohrer U, Santoro R, Längst G, Grummt I (Sep 2001). "NoRC--a novel member of mammalian ISWI-containing chromatin remodeling machines". The EMBO Journal. 20 (17): 4892–900. PMC 125270 . PMID 11532953. doi:10.1093/emboj/20.17.4892.
↑ "Entrez Gene: BAZ2A bromodomain adjacent to zinc finger domain, 2A".

External links

Human BAZ2A genome location and BAZ2A gene details page in the UCSC Genome Browser.

Further reading

Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Apr 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research. 4 (2): 141–50. PMID 9205841. doi:10.1093/dnares/4.2.141.
Zhou Y, Santoro R, Grummt I (Sep 2002). "The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription". The EMBO Journal. 21 (17): 4632–40. PMC 126197 . PMID 12198165. doi:10.1093/emboj/cdf460.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (Aug 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–5. PMC 514446 . PMID 15302935. doi:10.1073/pnas.0404720101.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. PMID 17081983. doi:10.1016/j.cell.2006.09.026.
Szafranski K, Schindler S, Taudien S, Hiller M, Huse K, Jahn N, Schreiber S, Backofen R, Platzer M (2007). "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns". Genome Biology. 8 (8): R154. PMC 2374985 . PMID 17672918. doi:10.1186/gb-2007-8-8-r154.

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