Aurotioprol

Aurotioprol
Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	Intramuscular injection
ATC code	M01CB05 (WHO)
Identifiers
IUPAC name Sodium aurothiopropanolsulfonate
PubChem CID	44144564
ChemSpider	8628381
UNII	G7097J63E9
ECHA InfoCard	100.043.971
Chemical and physical data
Formula	C₃H₆AuNaO₄S₂
Molar mass	390.16
3D model (JSmol)	Interactive image
SMILES C(C(CS(=O)(=O)[O-])O)[S-].[Na+].[Au+]
InChI InChI=1S/C3H8O4S2.Au.Na/c4-3(1-8)2-9(5,6)7;;/h3-4,8H,1-2H2,(H,5,6,7);;/q;2*+1/p-2 Key:KBWWFTIQBJUOQR-UHFFFAOYSA-L
(verify)

Aurotioprol is a gold salt used as an antirheumatic agent.^[1]^[2]

References

↑ Perrier, P.; Raffoux, C.; Thomas, P.; Tamisier, J. N.; Busson, M.; Gaucher, A.; Streiff, F. (1985). "HLA antigens and toxic reactions to sodium aurothiopropanol sulphonate and D-penicillamine in patients with rheumatoid arthritis". Annals of the rheumatic diseases. 44 (9): 621–624. PMC 1001721 . PMID 3876081. doi:10.1136/ard.44.9.621.
↑ Veys, E. M.; Mielants, H.; Verbruggen, G. (1987). "Goldsalts, levamisole and D-penicillamine as first choice slow-acting antirheumatic drugs in rheumatoid arthritis--a long-term follow-up study". Clinical and experimental rheumatology. 5 (2): 111–116. PMID 3608266.

Specific antirheumatic products / DMARDs (M01C)
Quinolines	Oxycinchophen
Gold preparations	Sodium aurothiomalate Sodium aurothiosulfate Auranofin Aurothioglucose Aurotioprol
Other	Penicillamine #/Bucillamine Chloroquine #/Hydroxychloroquine Leflunomide Sulfasalazine # antifolate (Methotrexate #) thiopurine (Azathioprine) #
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

Gold compounds

Gold(-I)

Gold(I)

Organogold(I) compounds	(AuC₆H₂(CH₃)₃)₅

Gold(II)

Gold(I,III)

Gold(III)

Gold(V)

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.