Anthony Zador
| Anthony Zador | |
|---|---|
| Nationality | American |
| Fields | Neuroscience |
| Institutions | Cold Spring Harbor Laboratory |
| Education | B.A., University of California, Berkeley; MD-PhD, Yale University |
| Doctoral advisor | Christof Koch |
| Other academic advisors | Charles F. Stevens |
| Known for | Molecular approaches to connectomics |
Anthony M. Zador is an American neuroscientist and the Alle Davis Harris Professor of Biology and Chair of Neuroscience at Cold Spring Harbor Laboratory.[1] He is a co-founder of the Computational and Systems Neuroscience (COSYNE) conference. Dr. Zador's research has focused on understanding the circuits of the auditory cortex in rodents. More recently, he proposed a new approach to connectome mapping using the methods of molecular biology, which may dramatically decrease the cost and improve the speed of mapping neuronal circuits at the single cell level.[2][3]
Biography
Anthony Zador received a B.A. at the UC, Berkeley and MD/PhD from Yale University, under the supervision of Tom Brown and Christof Koch at Caltech. He carried out postdoctoral research at the Salk Institute with Chuck Stevens before assuming a faculty position at Cold Spring Harbor Laboratory.
At CSHL, together with Zachary Mainen, he pioneered the use of quantitative behavioral paradigms in rodents to study perception and cognition.[4] In 2012, Dr. Zador a proposed a method harnessing advances in DNA sequencing to map neural circuits with much higher throughput than conventional microscopy-based approaches.[5] This method promises to reconstruct the connectivity matrices of entire brains with single cell resolution. So far, a variant of this approach has been applied to map the projection patterns single locus coeruleus neurons at the mesoscale.[3][6]
Zador was recognized as a 2015 Foreign Policy Global Thinker.[7] He is also an occasional columnist for the Observer, writing on the intersection of science, technology and policy.[8]
References
- ↑ "CSHL Anthony Zador". Cold Spring Harbor Laboratory. Retrieved 14 December 2016.
- ↑ "Sequencing the Connectome: Will DNA Bar Codes and a Sneaky Virus Change the Way Scientists Map the Brain?". Scientific American. 23 October 2012. Retrieved 14 December 2016.
- 1 2 "Mapmaking with barcoded neurons". Nature Methods. 31 October 2016. Retrieved 14 December 2016.
- ↑ "Neuroscience: The rat pack". Nature. 19 May 2010. Retrieved 14 December 2016.
- ↑ Zador AM, Dubnau J, Oyibo HK, Zhan H, Cao G, Peikon ID (2012). "Sequencing the Connectome". PLOS Biology. doi:10.1371/journal.pbio.1001411.
- ↑ Kebschull JM, Garcia da Silva P, Reid AP, Peikon ID, Albeanu DF, Zador AM (2016). "High-Throughput Mapping of Single-Neuron Projections by Sequencing of Barcoded RNA". Neuron. 91 (5): 975–87. doi:10.1016/j.neuron.2016.07.036.
- ↑ "The Year of Changing Our Minds: The Leading Global Thinkers of 2015". Foreign Policy.
- ↑ "Government’s ‘Golden Fleece’ Is Now Humanity’s Golden Goose".