Anthony Gill (professor)

Anthony J Gill is an Australian pathologist, professor and medical researcher. He is professor of surgical pathology at the University of Sydney and the chairman of Australian Pancreatic Cancer Genome Initiative.^[1][2] Most of his research is focused on translating the improved understanding of cancer gained at the basic science level into clinically useful diagnostic tests which can be applied in the routine surgical pathology laboratory.^[3] Gill is best known for his description of the class of malignancies now known as succinate dehydrogenase deficient (SDH deficient) - including SDH deficient Renal Carcinoma and SDH deficient Gastrointestinal Stromal Tumour (GIST).^[4][5] He founded and leads the Cancer Diagnosis and Pathology Research Group at the University of Sydney and Kolling Institute of Medical Research.^[6] In 2017 he was presented with the Ramzi Cotran young investigator award by the United States and Canadian Academy of Pathology in recognition of his research.^[7]

Awards and honors

• 1996 - The Royal North Shore Hospital Medal
• 2011 - The Benjamin Castleman Award^[8]
• 2011 - The Sir John Loewenthal Medal
• 2012 - NSW Cancer Institute Wildfire Award
• 2013 - NSW Premier’s Award for Excellence in Translational Cancer Research
• 2014 - The Sir Zelman Cowen Universities Prize for discovery in Medical Research
• 2015 - NSW Cancer Institute Wildfire Award
• 2017 - "USCAP Ramzi Cotran Award". 
• 2017 - "International Academy of Pathology Vincent McGovern Lecture". 

Publications

• Gill AJ, Clarkson A, Gimm O, Keil J, Dralle H, Howell VM, Marsh DJ. Loss of nuclear expression of parafibromin distinguishes parathyroid carcinomas and Hyperparathyroidsim-Jaw Tumor (HPT-JT) syndrome related adenomas from sporadic parathyroid adenomas and hyperplasias American Journal of Surgical Pathology 2006 30:1140-1149
• Gill AJ, Chou A, Vilain R, Clarkson A, Lui M, Jin R, Tobias V, Samra J, Goldstein D, Smith C, Sioson L, Parker N, Smith RC, Sywak M, Sidhu SB, Ma Wyatt J, Robinson BG, Benn DE, Clifton-Bligh RJ Immunohistochemistry for SDHB divides Gastrointestinal Stromal Tumors (GISTs) into two distinct types American Journal of Surgical Pathology 2010;34:636-44
• Gill AJ, Benn DE, Chou A, Clarkson A, Muljono A, Meyer-Rochow G, Richardson A-L, Sidhu SB, Robinson BG, Clifton-Bligh RJ Immunohistochemistry for SDHB triages genetic testing of SDHB, SDHC and SDHD in paraganglioma-phaeochromocytoma syndromes Human Pathology 2010 41:805-814
• Gill AJ, Pachter NS, Clarkson A, Tucker KM, Winship I, Benn DE, Robinson BG, Clifton-Bligh R Renal Tumors and Hereditary Pheochromoytoma-Paraganglioma Syndrome New England Journal of Medicine 2011 364; 9:885-886
• Gill AJ, Chou A, Vilain RE, Clifton-Bligh RJ “Pediatric type” Gastrointestinal stromal tumors are SDHB negative (“type 2”) GISTs American Journal of Surgical Pathology 2011 35:1245–1247
• Gill AJ, Pachter NS, Chou A, Young B, Clarkson A, Tucker KM, Winship IM, Earls P, Benn DE, Robinson BG, Fleming S, Clifton-Bligh RH The renal tumors associated with germline SDHB mutation show distinctive morphology American Journal of Surgical Pathology 2011 35:1578-1585
• Dwight T, Benn DE, Clarkson A, Vilain R, Lipton L, Robinson BG, Clifton-Bligh RJ, Gill AJ Loss of SDHA expression identifies SDHA mutations in succinate dehydrogenase deficient gastrointestinal stromal tumors American Journal of Surgical Pathology 2013; 37:226–233
• Gill AJ, Hes O, Papathomas T, Sedivcova M, Tan PH, Agaimy A, Andresen PA, Kedziora A, Clarkson A, Toon CW, Sioson L, Watson N, Chou A, Paik J, Clifton-Bligh RJ, Robinson BG, Benn DE, Hills H, Maclean F, Niemeijer ND, Vlatkovic L, Hartmann A, Corssmit EPM, van Leenders GJLH, Pryzbycin C, McKenney JK, Magi-Galluzzi C, Yilmaz A, Yu D, Nicoll KD, Yong JL, Sibony M, Yakirevich E, Fleming S, Chow CW, Miettinen M, Michal M, Trpkov Succinate dehydrogenase (SDH) deficient renal carcinoma – a morphologically distinct entity: A clinicopathologic series of 36 tumors from 27 patients American Journal of Surgical Pathology 2014; 38:1588–1602
• Farzin M, Toon CW, Clarkson A, Sioson L, Watson N, Andrici J, Gill AJ Loss of expression of BAP1 predicts longer survival in mesothelioma Pathology 2015; 47:302-307
• Andrici J, Sheen A, Sioson L, Wardell K, Clarkson A, Watson N, Ahadi MS, Farzin M, Toon CW, Gill AJ Loss of expression of BAP1 is a useful adjunct which strongly supports the diagnosis of mesothelioma in effusion cytology Modern Pathology 2015; 28:1360–1368
• Harrison WJ, Andrici J, Maclean F, Madadi-Ghahan R, Farzin M, Sioson L, Toon CW, Clarkson A, Watson N, Pickett J, Field M, Crook A, Tucker K, Goodwin A, Anderson L, Srinivasan B, Grossman P, Martinek P, Ondic O, Hes O, Trpkov K, Clifton-Bligh RJ, Dwight T, Gill AJ Fumarate hydratase deficient uterine leiomyomas occur in both the syndromic and sporadic settings American Journal of Surgical Pathology 2016; 40:599–607
• Trpkov K, Hess O, Agaimy A, Bonert M, Martinek P, Magi-Galluzzi C, Kristiansen G, Lüders C, Nesi G, Comperat E, Sibony M, Berney DM, Mehra R, Brimo F, Hartman A, Husain A, Frizzell N, Hills K, Maclean F, Srinivasan B, Gill AJ Fumarate Hydratase-deficient Renal Cell Carcinoma is Strongly Correlated with Fumarate Hydratase Mutation and Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome American Journal of Surgical Pathology 2016;40:865–875

References