Aminoadipate-semialdehyde dehydrogenase

AASDH
Identifiers
AliasesAASDH, ACSF4, LYS2, NRPS1098, NRPS998, aminoadipate-semialdehyde dehydrogenase
External IDsMGI: 2442517 HomoloGene: 71711 GeneCards: AASDH
EC number1.2.1.31
Orthologs
SpeciesHumanMouse
Entrez

132949

231326

Ensembl

ENSG00000157426

ENSMUSG00000055923

UniProt

Q4L235

Q80WC9

RefSeq (mRNA)

NM_173765

RefSeq (protein)

NP_776126

Location (UCSC)Chr 4: 56.34 – 56.39 MbChr 5: 76.87 – 76.91 Mb
PubMed search[1][2]
Wikidata
View/Edit HumanView/Edit Mouse

Aminoadipate-semialdehyde dehydrogenase is a protein that in humans is encoded by the AASDH gene. [3]

Function

This gene encodes a member of the non-ribosome peptide syntesase (NRPS) enzyme family. The encoded protein contains an AMP-binding domain, PP-binding (phosphopantetheine, or pantetheine 4'phosphate-binding) domain and the Pyrrolo-quinoline quinon (PQQ) binding domain. The protein is expressed in several adult tissues.

References

  1. ↑ "Human PubMed Reference:".
  2. ↑ "Mouse PubMed Reference:".
  3. ↑ "Entrez Gene: Aminoadipate-semialdehyde dehydrogenase". Retrieved 2017-01-02.

Further reading

  • Wang L, Jil C, Xu Y, Xu J, Dai J, Wu Q, Wu M, Zou X, Sun L, Gu S, Xie Y, Mao Y (2005). "Cloning and characterization of a novel human homolog* of mouse U26, a putative PQQ-dependent AAS dehydrogenase". Mol. Biol. Rep. 32 (1): 47–53. PMID 15865210. 

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.