Adenovirus early region 1A

Adenovirus early region 1A (E1a or E1A) is a gene expressed during adenovirus replication to produce a variety of (E1A) proteins.[1]

It has been considered an oncogene.[2]

It can behave as a tumour suppressor gene.[3][4]

References

  1. ↑ "Introduction To Ad5 E1A".
  2. ↑ "Adenovirus E1A Oncogene Expression in Tumor Cells Enhances Killing by TNF-Related Apoptosis-Inducing Ligand (TRAIL)". 2000.
  3. ↑ "E1A as a Tumor Suppressor Gene".
  4. ↑ "Adenovirus-5 E1A: paradox and paradigm". Nat Rev Mol Cell Biol. 3 (6): 441–52. Jun 2002. PMID 12042766. doi:10.1038/nrm827.



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