ASTL

Identifiers

ASTL, SAS1B, astacin-like metallo-endopeptidase (M12 family), astacin like metalloendopeptidase

External IDs

Gene ontology
Molecular function	• peptidase activity • glutamic-type peptidase activity • metallopeptidase activity • hydrolase activity • metalloendopeptidase activity • zinc ion binding • aspartic-type peptidase activity • metal ion binding
Cellular component	• plasma membrane • transport vesicle • cytoplasm • membrane • cytoplasmic vesicle • cortical granule
Biological process	• fertilization • positive regulation of protein processing • prevention of polyspermy • proteolysis • negative regulation of binding of sperm to zona pellucida • single fertilization • cell adhesion
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


431705


215095


ENSG00000188886


ENSMUSG00000050468


Q6HA08


Q6HA09

RefSeq (mRNA)


NM_001002036


NM_001291003 NM_172539

RefSeq (protein)


NP_001002036


NP_001277932 NP_766127

Location (UCSC)

PubMed search

^[1]

^[2]

Astacin-like metallo-endopeptidase (M12 family) is a protein that in humans is encoded by the ASTL gene.^[3]^[4]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ "Entrez Gene: Astacin-like metallo-endopeptidase (M12 family)".
↑ Quesada V, Sánchez LM, Alvarez J, López-Otín C (2004). "Identification and characterization of human and mouse ovastacin: a novel metalloproteinase similar to hatching enzymes from arthropods, birds, amphibians, and fish". J. Biol. Chem. 279 (25): 26627–34. PMID 15087446. doi:10.1074/jbc.M401588200.

Human ASTL genome location and ASTL gene details page in the UCSC Genome Browser.

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