ARL8A

ARL8A

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1ZD9, 2H18, 4ILE

Identifiers

ARL8A, ARL10B, GIE2, ADP ribosylation factor like GTPase 8A

External IDs

MGI: 1915974 HomoloGene: 23600 GeneCards: ARL8A

Gene ontology
Molecular function	• nucleotide binding • alpha-tubulin binding • GTP binding • protein binding • beta-tubulin binding • GTPase activity
Cellular component	• cytoplasm • spindle midzone • lysosomal membrane • endosome • lysosome • midbody • extracellular exosome • intracellular • membrane • late endosome membrane • plasma membrane • azurophil granule membrane • ficolin-1-rich granule membrane
Biological process	• cell division • small GTPase mediated signal transduction • cell cycle • chromosome segregation • neutrophil degranulation
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


127829


68724


ENSG00000143862


ENSMUSG00000026426


Q96BM9


Q8VEH3

RefSeq (mRNA)


NM_138795 NM_001256129


NM_026823

RefSeq (protein)


NP_001243058 NP_620150


NP_081099

Location (UCSC)

Chr 1: 202.13 – 202.14 Mb

Chr 1: 135.15 – 135.16 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

ADP-ribosylation factor-like protein 8A is a protein that in humans is encoded by the ARL8A gene.^[3]^[4]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Bonaldo MF, Lennon G, Soares MB (May 1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. PMID 8889548. doi:10.1101/gr.6.9.791.
↑ "Entrez Gene: ARL8A ADP-ribosylation factor-like 8A".

External links

Human ARL8A genome location and ARL8A gene details page in the UCSC Genome Browser.

Further reading

Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature. 441 (7091): 315–21. PMID 16710414. doi:10.1038/nature04727.
Hofmann I, Munro S (2006). "An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility.". J. Cell. Sci. 119 (Pt 8): 1494–503. PMID 16537643. doi:10.1242/jcs.02958.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
Okai T, Araki Y, Tada M, et al. (2005). "Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation.". J. Cell. Sci. 117 (Pt 20): 4705–15. PMID 15331635. doi:10.1242/jcs.01347.
Secombe J, Parkhurst SM (2004). "Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein.". J. Biol. Chem. 279 (17): 17126–33. PMID 14871887. doi:10.1074/jbc.M310097200.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.

PDB gallery

1zd9: Structure of human ADP-ribosylation factor-like 10B

2al7: Structure Of Human ADP-Ribosylation Factor-Like 10C

2h18: Structure of human ADP-ribosylation factor-like 10B (ARL10B)

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