ARFIP2
Arfaptin-2 is a protein that in humans is encoded by the ARFIP2 gene.[3][4][5]
Interactions
ARFIP2 has been shown to interact with Arf6,[6][7] ARF3,[4] ARF5[4][7] and RAC1.[3][7][8]
References
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- 1 2 Van Aelst L, Joneson T, Bar-Sagi D (October 1996). "Identification of a novel Rac1-interacting protein involved in membrane ruffling". EMBO J. 15 (15): 3778–86. PMC 452058
. PMID 8670882. - 1 2 3 Kanoh H, Williger BT, Exton JH (April 1997). "Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation factor, is recruited to Golgi membranes". J Biol Chem. 272 (9): 5421–9. PMID 9038142. doi:10.1074/jbc.272.9.5421.
- ↑ "Entrez Gene: ARFIP2 ADP-ribosylation factor interacting protein 2 (arfaptin 2)".
- ↑ D'Souza-Schorey, C; Boshans R L; McDonough M; Stahl P D; Van Aelst L (September 1997). "A role for POR1, a Rac1-interacting protein, in ARF6-mediated cytoskeletal rearrangements". EMBO J. ENGLAND. 16 (17): 5445–54. ISSN 0261-4189. PMC 1170175 . PMID 9312003. doi:10.1093/emboj/16.17.5445.
- 1 2 3 Shin, O H; Exton J H (August 2001). "Differential binding of arfaptin 2/POR1 to ADP-ribosylation factors and Rac1". Biochem. Biophys. Res. Commun. United States. 285 (5): 1267–73. ISSN 0006-291X. PMID 11478794. doi:10.1006/bbrc.2001.5330.
- ↑ Tarricone, C; Xiao B; Justin N; Walker P A; Rittinger K; Gamblin S J; Smerdon S J (May 2001). "The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways". Nature. England. 411 (6834): 215–9. ISSN 0028-0836. PMID 11346801. doi:10.1038/35075620.
Further reading
- D'Souza-Schorey C, Boshans RL, McDonough M, et al. (1997). "A role for POR1, a Rac1-interacting protein, in ARF6-mediated cytoskeletal rearrangements.". EMBO J. 16 (17): 5445–54. PMC 1170175 . PMID 9312003. doi:10.1093/emboj/16.17.5445.
- Tarricone C, Xiao B, Justin N, et al. (2001). "The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways.". Nature. 411 (6834): 215–9. PMID 11346801. doi:10.1038/35075620.
- Shin OH, Exton JH (2001). "Differential binding of arfaptin 2/POR1 to ADP-ribosylation factors and Rac1.". Biochem. Biophys. Res. Commun. 285 (5): 1267–73. PMID 11478794. doi:10.1006/bbrc.2001.5330.
- Peters PJ, Ning K, Palacios F, et al. (2002). "Arfaptin 2 regulates the aggregation of mutant huntingtin protein.". Nat. Cell Biol. 4 (3): 240–5. PMID 11854752. doi:10.1038/ncb761.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
- Lu L, Hong W (2004). "Interaction of Arl1-GTP with GRIP domains recruits autoantigens Golgin-97 and Golgin-245/p230 onto the Golgi.". Mol. Biol. Cell. 14 (9): 3767–81. PMC 196566 . PMID 12972563. doi:10.1091/mbc.E03-01-0864.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
- Rangone H, Pardo R, Colin E, et al. (2005). "Phosphorylation of arfaptin 2 at Ser260 by Akt Inhibits PolyQ-huntingtin-induced toxicity by rescuing proteasome impairment.". J. Biol. Chem. 280 (23): 22021–8. PMID 15809304. doi:10.1074/jbc.M407528200.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature. 437 (7062): 1173–8. PMID 16189514. doi:10.1038/nature04209.
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External links
- Human ARFIP2 genome location and ARFIP2 gene details page in the UCSC Genome Browser.
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