ANKRD23
| ANKRD23 | |||||||||||||||||
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| Identifiers | |||||||||||||||||
| Aliases | ANKRD23, DARP, MARP3, ankyrin repeat domain 23 | ||||||||||||||||
| External IDs | MGI: 1925571 HomoloGene: 14025 GeneCards: ANKRD23 | ||||||||||||||||
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| Orthologs | |||||||||||||||||
| Species | Human | Mouse | |||||||||||||||
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| Ensembl | |||||||||||||||||
| UniProt | |||||||||||||||||
| RefSeq (mRNA) | |||||||||||||||||
| RefSeq (protein) | |||||||||||||||||
| Location (UCSC) | Chr 2: 96.82 – 96.86 Mb | Chr 1: 36.53 – 36.54 Mb | |||||||||||||||
| PubMed search | [1] | [2] | |||||||||||||||
| Wikidata | |||||||||||||||||
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Ankyrin repeat domain-containing protein 23 is a protein that in humans is encoded by the ANKRD23 gene.[3][4]
This gene is a member of the muscle ankyrin repeat protein (MARP) family and encodes a protein with four tandem ankyrin-like repeats. The protein is localized to the nucleus, functioning as a transcriptional regulator. Expression of this protein is induced during recovery following starvation.[4]
Interactions
ANKRD23 has been shown to interact with Titin[5] and MYPN.[5]
References
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ Ikeda K, Emoto N, Matsuo M, Yokoyama M (Feb 2003). "Molecular identification and characterization of a novel nuclear protein whose expression is up-regulated in insulin-resistant animals". J Biol Chem. 278 (6): 3514–20. PMID 12456686. doi:10.1074/jbc.M204563200.
- 1 2 "Entrez Gene: ANKRD23 ankyrin repeat domain 23".
- 1 2 Miller, Melanie K; Bang Marie-Louise; Witt Christian C; Labeit Dietmar; Trombitas Charles; Watanabe Kaori; Granzier Henk; McElhinny Abigail S; Gregorio Carol C; Labeit Siegfried (Nov 2003). "The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules". J. Mol. Biol. England. 333 (5): 951–64. ISSN 0022-2836. PMID 14583192. doi:10.1016/j.jmb.2003.09.012.
External links
- Human ANKRD23 genome location and ANKRD23 gene details page in the UCSC Genome Browser.
Further reading
- Hillier LW; Graves TA; Fulton RS; et al. (2005), "Generation and annotation of the DNA sequences of human chromosomes 2 and 4", Nature, 434 (7034): 724–31, PMID 15815621, doi:10.1038/nature03466
- Gerhard DS; Wagner L; Feingold EA; et al. (2004), "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)", Genome Res., 14 (10B): 2121–7, PMC 528928
, PMID 15489334, doi:10.1101/gr.2596504 - Nagueh SF; Shah G; Wu Y; et al. (2005), "Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy", Circulation, 110 (2): 155–62, PMID 15238456, doi:10.1161/01.CIR.0000135591.37759.AF
- Ota T; Suzuki Y; Nishikawa T; et al. (2004), "Complete sequencing and characterization of 21,243 full-length human cDNAs", Nat. Genet., 36 (1): 40–5, PMID 14702039, doi:10.1038/ng1285
- Miller MK; Bang ML; Witt CC; et al. (2003), "The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules", J. Mol. Biol., 333 (5): 951–64, PMID 14583192, doi:10.1016/j.jmb.2003.09.012
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003), "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences", Proc. Natl. Acad. Sci. U.S.A., 99 (26): 16899–903, PMC 139241 , PMID 12477932, doi:10.1073/pnas.242603899
- Dias Neto E; Correa RG; Verjovski-Almeida S; et al. (2000), "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags", Proc. Natl. Acad. Sci. U.S.A., 97 (7): 3491–6, PMC 16267 , PMID 10737800, doi:10.1073/pnas.97.7.3491
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