AMELY
| AMELY | |||||||||||||||||
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| Identifiers | |||||||||||||||||
| Aliases | AMELY, AMGL, AMGY, amelogenin, Y-linked | ||||||||||||||||
| External IDs | OMIM: 410000 MGI: 88005 HomoloGene: 47996 GeneCards: AMELY | ||||||||||||||||
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| Orthologs | |||||||||||||||||
| Species | Human | Mouse | |||||||||||||||
| Entrez | |||||||||||||||||
| Ensembl | |||||||||||||||||
| UniProt | |||||||||||||||||
| RefSeq (mRNA) | |||||||||||||||||
| RefSeq (protein) | |||||||||||||||||
| Location (UCSC) | Chr Y: 6.87 – 6.87 Mb | Chr X: 169.18 – 169.19 Mb | |||||||||||||||
| PubMed search | [1] | [2] | |||||||||||||||
| Wikidata | |||||||||||||||||
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Amelogenin, Y isoform is a protein that in humans is encoded by the AMELY (amelogenin, Y-linked) gene.[3][4]
AMELY is a gene which encodes a form of amelogenin found on the Y chromosome. Amelogenin is a member of a family of extracellular matrix proteins. They are involved in biomineralization during tooth enamel development. Mutations in the related AMELX gene on the X chromosome cause X-linked amelogenesis imperfecta.[4]
See also
References
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ Nakahori Y, Takenaka O, Nakagome Y (February 1991). "A human X-Y homologous region encodes "amelogenin"". Genomics. 9 (2): 264–9. PMID 2004775. doi:10.1016/0888-7543(91)90251-9.
- 1 2 "Entrez Gene: amelogenin".
External links
- Human AMELY genome location and AMELY gene details page in the UCSC Genome Browser.
Further reading
- Nakahori Y, Tamura T, Nagafuchi S, et al. (1991). "Molecular cloning and mapping of 10 new probes on the human Y chromosome.". Genomics. 9 (4): 765–9. PMID 2037302. doi:10.1016/0888-7543(91)90373-M.
- Lau EC, Mohandas TK, Shapiro LJ, et al. (1989). "Human and mouse amelogenin gene loci are on the sex chromosomes.". Genomics. 4 (2): 162–8. PMID 2737677. doi:10.1016/0888-7543(89)90295-4.
- Skaletsky H, Kuroda-Kawaguchi T, Minx PJ, et al. (2003). "The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes.". Nature. 423 (6942): 825–37. PMID 12815422. doi:10.1038/nature01722.
- Jobling MA, Lo IC, Turner DJ, et al. (2007). "Structural variation on the short arm of the human Y chromosome: recurrent multigene deletions encompassing Amelogenin Y". Hum. Mol. Genet. 16 (3): 307–16. PMC 2590852
. PMID 17189292. doi:10.1093/hmg/ddl465. - Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. PMC 528928 . PMID 15489334. doi:10.1101/gr.2596504.
- Salido EC, Yen PH, Koprivnikar K, et al. (1992). "The human enamel protein gene amelogenin is expressed from both the X and the Y chromosomes". Am. J. Hum. Genet. 50 (2): 303–16. PMC 1682460 . PMID 1734713.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
- Chen AP, Chen Y, Wang HP, et al. (2007). "[Types and frequencies of variants in Amelogenin gene in Chinese population]". Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 24 (6): 615–9. PMID 18067069.
- Barbe L, Lundberg E, Oksvold P, et al. (2008). "Toward a confocal subcellular atlas of the human proteome". Mol. Cell Proteomics. 7 (3): 499–508. PMID 18029348. doi:10.1074/mcp.M700325-MCP200.
- Yong RY, Gan LS, Chang YM, Yap EP (2007). "Molecular characterization of a polymorphic 3-Mb deletion at chromosome Yp11.2 containing the AMELY locus in Singapore and Malaysia populations". Hum. Genet. 122 (3–4): 237–49. PMID 17588179. doi:10.1007/s00439-007-0389-0.
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