6-Hydroxyflavone

6-Hydroxyflavone
Names


IUPAC name 6-hydroxy-2-phenylchromen-4-one
Other names 6-Monohydroxyflavone; 6-Hydroxy-2-phenyl-4-benzopyrone
Identifiers
CAS Number	6665-83-4^N
3D model (JSmol)	Interactive image Interactive image
ChemSpider	65233^Y
ECHA InfoCard	100.027.005
EC Number	229-704-8
KEGG	C14137^Y
PubChem CID	72279
InChI InChI=1S/C15H10O3/c16-11-6-7-14-12(8-11)13(17)9-15(18-14)10-4-2-1-3-5-10/h1-9,16H^Y Key: GPZYYYGYCRFPBU-UHFFFAOYSA-N^Y InChI=1/C15H10O3/c16-11-6-7-14-12(8-11)13(17)9-15(18-14)10-4-2-1-3-5-10/h1-9,16H Key: GPZYYYGYCRFPBU-UHFFFAOYAV
SMILES C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=CC(=C3)O O=C\1c3c(O/C(=C/1)c2ccccc2)ccc(O)c3
Properties
Chemical formula	C₁₅H₁₀O₃
Molar mass	238.24 g·mol⁻¹
Melting point	234 to 236 °C (453 to 457 °F; 507 to 509 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

6-Hydroxyflavone is a flavone, a type of chemical compound. It is one of the noncompetitive inhibitors of cytochrome P450 2C9. It is reported in leaves of Barleria prionitis Linn. (a common Acanthaceae from India).^[1] 6-Hydroxyflavone may have a potential as a therapeutic drug capable for the treatment of anxiety-like disorders.^[2]

References

↑ Medicinal plants, Chemistry and properties by M Daniel.
↑ "GABAA receptor subtype selectivity underlying anxiolytic effect of 6-hydroxyflavone". ScienceDirect. Retrieved 2011-06-12.

External links

6-hydroxy flavone on Plant Metabolic Network

Flavones and their conjugates

Aglycones

Monohydroxyflavone	6-Hydroxyflavone
Dihydroxyflavones	Chrysin 4',7-Dihydroxyflavone 7,8-Dihydroxyflavone
Trihydroxyflavones	Apigenin Baicalein Norwogonin
Tetrahydroxyflavones	Isoscutellarein Luteolin Norartocarpetin Scutellarein
Pentahydroxyflavones	6-Hydroxyluteolin Hypolaetin Tricetin
O-methylated flavones	Acacetin Alnetin Artocarpetin Chrysoeriol Cirsilineol Cirsiliol Cirsimaritin Diosmetin Eupatilin Genkwanin Hispidulin Nepetin Nobiletin Oroxylin A Pratol Salvigenin Sinensetin Tangeritin Techtochrysin Tricin Wogonin Zapotin

Glycosides

of apigenin	Apiin Apigetrin Isovitexin Rhoifolin Saponarin Schaftoside Vicenin-2 Vitexin
of baicalein	Baicalin Tetuin
of hypolaetin	Hypolaetin 8-glucoside Hypolaetin 8-glucuronide
of luteolin	Cynaroside Isoorientin Orientin Veronicastroside Luteolin-7-O-glucuronide

Giraldiin A and B
Nepitrin
Oroxindin
Scutellarin

Acetylated

Artocarpetin A
Artoindonesianin P

Sulfated glycosides

Theograndin I and II

Polymers

Amentoflavone

Drugs

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