23S rRNA pseudouridine2604 synthase
| 23S rRNA pseudouridine2604 synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 5.4.99.21 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
23S rRNA pseudouridine2604 synthase (EC 5.4.99.21, RluF, YjbC) is an enzyme with systematic name 23S rRNA-uridine2604 uracil mutase.[1][2][3] This enzyme catalyses the following chemical reaction
- 23S rRNA uridine2604 23S rRNA pseudouridine2604
The enzyme can, to a small extent, also react with uridine2605.
References
- ↑ Del Campo, M.; Kaya, Y.; Ofengand, J. (2001). "Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli". RNA. 7: 1603–1615. PMC 1370202
. PMID 11720289. - ↑ Alian, A.; DeGiovanni, A.; Griner, S.L.; Finer-Moore, J.S.; Stroud, R.M. (2009). "Crystal structure of an RluF-RNA complex: a base-pair rearrangement is the key to selectivity of RluF for U2604 of the ribosome". J. Mol. Biol. 388: 785–800. PMC 2796871 . PMID 19298824. doi:10.1016/j.jmb.2009.03.029.
- ↑ Sunita, S.; Zhenxing, H.; Swaathi, J.; Cygler, M.; Matte, A.; Sivaraman, J. (2006). "Domain organization and crystal structure of the catalytic domain of E. coli RluF, a pseudouridine synthase that acts on 23S rRNA". J. Mol. Biol. 359: 998–1009. PMID 16712869. doi:10.1016/j.jmb.2006.04.019.
External links
- 23S rRNA pseudouridine2604 synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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