2-Quinolone

2-Quinolone
Names
Other names carbostyril, 1,2-dihydro-2-oxoquinoline, 1H-quinolin-2-one
Identifiers
CAS Number	59-31-4
3D model (JSmol)	Interactive image
ChEBI	CHEBI:16365
ChemSpider	5816
EC Number	200-420-6
KEGG	C06338
PubChem CID	6038
UNII	803BHY7QWU
InChI InChI=1S/C9H7NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-6H,(H,10,11) Key: LISFMEBWQUVKPJ-UHFFFAOYSA-N
SMILES C1=CC=C2C(=C1)C=CC(=O)N2
Properties
Chemical formula	C₉H₇NO
Molar mass	145.16 g·mol⁻¹
Appearance	solid
Melting point	199.5 °C (391.1 °F; 472.6 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

2-Quinolone is an organic compound related structurally to quinoline. It is the majority tautomer in equilibrium with 2-quinolinol. The compound can be classified as a cyclic amide, and as such is used as a isostere for peptides and other pharmaceutically-inspired targets.^[1] The isomer 4-quinolone is the parent of a large class of quinolone antibiotics.

2-Quinolone and its tautomer 2-hydroxylquinoline.

References

↑ Tashima, Toshihiko (2015). "The structural use of carbostyril in physiologically active substances". Bioorganic & Medicinal Chemistry Letters. 25: 3415–3419. doi:10.1016/j.bmcl.2015.06.027.

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