2,4-Dichlorobenzyl alcohol

2,4-Dichlorobenzyl alcohol
Names
IUPAC name
(2,4-Dichlorophenyl)methanol
Other names
Dybenal
Rapidosept
Myacide SP
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.015.646
Properties
C7H6Cl2O
Molar mass 177.02 g·mol−1
Melting point 57 to 60 °C (135 to 140 °F; 330 to 333 K)
Boiling point 150 °C (302 °F; 423 K) 25 mmHg
Pharmacology
R02AA03 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

2,4-Dichlorobenzyl alcohol is a mild antiseptic, able to kill bacteria and viruses associated with mouth and throat infections. It is a common ingredient in throat lozenges such as Strepsils, Lorsept, and Gorpils. A low-pH throat lozenge containing dichlorobenzyl alcohol (1.2 mg) and amylmetacresol (0.6 mg) has been found to deactivate respiratory syncytial virus and SARS-Cov, but not adenovirus or rhinovirus.[1] A dentifrice containing 10% sodium benzoate and 0.3% dichlorobenzyl alcohol maintains antimicrobial activity for 5 to 10 minutes after brushing.[2]

It is an ingredient in the European product Neo Borocillina.[3]

References

  1. ↑ Oxford JS, Lambkin R, Gibb I, Balasingam S, Chan C, Catchpole A (2005). "A throat lozenge containing amyl meta cresol and dichlorobenzyl alcohol has a direct virucidal effect on respiratory syncytial virus, influenza A and SARS-CoV". Antiviral Chemistry & Chemotherapy. 16 (2): 129–34. PMID 15889535.
  2. ↑ Ostergaard E (1994). "Evaluation of the antimicrobial effects of sodium benzoate and dichlorobenzyl alcohol against dental plaque microorganisms. An in vitro study.". Acta Odontol Scand. 52 (6): 335–45. PMID 7887143. doi:10.3109/00016359409029031.
  3. ↑ "Neo Borocillina". drugs.com.
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