11β-Methyl-19-nortestosterone dodecylcarbonate

11β-Methyl-19-nortestosterone dodecylcarbonate
Clinical data
Routes of
administration
Oral, intramuscular injection
Identifiers
Synonyms 11β-MNTDC; CDB-4754
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
Formula C32H52O4
Molar mass 500.7588 g/mol
3D model (JSmol)

11β-Methyl-19-nortestosterone 17β-dodecylcarbonate (11β-MNTDC) (developmental code name CDB-4754) is a synthetic, orally active anabolic-androgenic steroid (AAS) and a derivative of 19-nortestosterone (nandrolone) that was developed by the Contraceptive Development Branch (CDB) of the National Institute of Child Health and Human Development (NICHD) and has not been marketed at this time.[1][2][3][4] It is an androgen ester – specifically, the C17β dodecylcarbonate ester of 11β-methyl-19-nortestosterone (11β-MNT) – and acts as a prodrug of 11β-MNT in the body.[1][2][3][4]

See also

References

  1. 1 2 Attardi BJ, Marck BT, Matsumoto AM, Koduri S, Hild SA (2011). "Long-term effects of dimethandrolone 17β-undecanoate and 11β-methyl-19-nortestosterone 17β-dodecylcarbonate on body composition, bone mineral density, serum gonadotropins, and androgenic/anabolic activity in castrated male rats". J. Androl. 32 (2): 183–92. PMID 20798389. doi:10.2164/jandrol.110.010371.
  2. 1 2 Attardi BJ, Hild SA, Koduri S, Pham T, Pessaint L, Engbring J, Till B, Gropp D, Semon A, Reel JR (2010). "The potent synthetic androgens, dimethandrolone (7α,11β-dimethyl-19-nortestosterone) and 11β-methyl-19-nortestosterone, do not require 5α-reduction to exert their maximal androgenic effects". J. Steroid Biochem. Mol. Biol. 122 (4): 212–8. PMC 2949447Freely accessible. PMID 20599615. doi:10.1016/j.jsbmb.2010.06.009.
  3. 1 2 Hild SA, Attardi BJ, Koduri S, Till BA, Reel JR (2010). "Effects of synthetic androgens on liver function using the rabbit as a model". J. Androl. 31 (5): 472–81. PMC 2943539Freely accessible. PMID 20378929. doi:10.2164/jandrol.109.009365.
  4. 1 2 Blye, Richard P., and Hyun K. Kim. "Nandrolone 17β-carbonates." U.S. Patent No. 7,820,642. 26 Oct. 2010.
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