1-Deoxynojirimycin
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| Names | |
|---|---|
| IUPAC name
(2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-triol | |
| Identifiers | |
| 3D model (JSmol) |
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| ChEBI | |
| ChemSpider | |
| ECHA InfoCard | 100.119.812 |
| KEGG | |
| PubChem CID |
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| Properties | |
| C6H13NO4 | |
| Molar mass | 163.17 g/mol |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
1-Deoxynojirimycin (DNJ), also called duvoglustat or moranolin,[1] is an alpha-glucosidase inhibitor, most commonly found in mulberry leaves. Although it can be obtained in small quantities by brewing an herbal tea from mulberry leaves, interest in commercial production has led to research on developing mulberry tea higher in DNJ,[2] and on alternate routes of production, such as via Bacillus species.[3]
See also
- Nojirimycin
- 1-Deoxygalactonojirimycin, a stereoisomer of 1-deoxynojirimycin
References
- ↑ KEGG: Deoxynojirimycin.
- ↑ Chaluntorn Vichasilp; et al. (2012). "Development of high 1-deoxynojirimycin (DNJ) content mulberry tea and use of response surface methodology to optimize tea-making conditions for highest DNJ extraction". LWT - Food Science and Technology. 45 (2): 226–232. doi:10.1016/j.lwt.2011.09.008.
- ↑ Onose, S; Ikeda, R; Nakagawa, K; Kimura, T; Yamagishi, K; Higuchi, O; Miyazawa, T (2013). "Production of the α-glycosidase inhibitor 1-deoxynojirimycin from Bacillus species". Food chemistry. 138 (1): 516–23. PMID 23265519. doi:10.1016/j.foodchem.2012.11.012.
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