Z12 small nucleolar RNA

Small nucleolar RNA SNORD104
Predicted secondary structure and sequence conservation of SNORND104
Identifiers
Symbol	SNORND104
Alt. Symbols	snoZ12; Z12
Rfam	RF00289
Other data
RNA type	Gene; snRNA; snoRNA; CD-box
Domain(s)	Eukaryota
GO	0006396 0005730
SO	0001263

Z12 small nucleolar RNA is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.^[1] It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. Z12 snoRNA belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.^[1]

References

External links

• Page for Z12 small nucleolar RNA at Rfam