Wylie Vale
| Wylie W. Vale, Jr. | |
|---|---|
| Born |
July 3, 1941 Houston, Texas |
| Died |
January 3, 2012 (aged 70) Hana, Hawaii |
| Citizenship | United States of America |
| Fields | Endocrinology |
| Institutions | Salk Institute |
| Alma mater | Rice University, Baylor College of Medicine |
| Doctoral advisor | Roger Guillemin |
| Known for | discovery of key neuroendocrine hormones[1] |
| Notable awards |
Fred Conrad Koch Award [2] Hans Selye award[3] |
Wylie Walker Vale Jr. (July 3, 1941 – January 3, 2012) was an American endocrinologist who helped identify hormones controlling basic bodily functions.[4][5]
Early life and education
Vale was born in Houston, Texas, on July 3, 1941. He completed a B.A. degree in biology at Rice University and obtained a Ph.D. in physiology and biochemistry from Baylor College of Medicine. He commenced employment at the Salk Institute for Biological Studies in San Diego, California, in 1970.[6]
Career
In collaboration with his advisor and mentor Roger Guillemin, Vale contributed to the discovery, isolation and identification of thyrotropin releasing hormone and gonadotropin-releasing hormone in the 1970s; work that led to the Nobel Prize for Guillemin.[7]
At the Salk Institute, Vale led efforts in identifying the group of hormones involved in human growth, reproduction and temperature.[8] His group discovered, isolated and identified corticotropin-releasing hormone (CRF/CRH) in 1981 and growth hormone releasing factor (GHRF) in 1982.[7]
Vale also founded two biotechnology companies, Neurocrine Biosciences and Acceleron Pharma.[7]
Vale was head of both the Clayton Foundation Laboratories for Peptide Biology and the Helen McLoraine Chair in Molecular Neurobiology at the Salk Institute.[6] He died in 2012.[6]
References
- ↑ Montminy, M.; Lee, K. -F.; Rivier, J. E.; Rivier, C.; Reichlin, S. (2012). "Wylie Vale: Neuroendocrine master". Proceedings of the National Academy of Sciences 109 (10): 3604–3605. doi:10.1073/pnas.1201696109. PMC 3309770. PMID 22355104.
- ↑ Crowley Jr, W. F. (1997). "Citation for the 1997 Fred Conrad Koch Award of the Endocrine Society to Wylie Vale". Endocrine Reviews 18 (4): 612–613. PMID 9267765.
- ↑ "Wylie W. Vale. Recipient of the 1994 Hans Selye Award". Annals of the New York Academy of Sciences 771: xii–xiv. 1995. doi:10.1111/j.1749-6632.1995.tb44664.x. PMID 8597388.
- ↑ Evans, R. (2012). "Wylie Walker Vale Jr (1941–2012)". Nature 483 (7391): 542. doi:10.1038/483542a.
- ↑ Stenvers, K. L.; Findlay, J. K. (2012). "Inhibins and activins: Towards the future. A tribute to the late Professor Wylie W. Vale". Molecular and Cellular Endocrinology 359 (1-2): 1. doi:10.1016/j.mce.2012.03.001. PMID 22406753.
- 1 2 3 "Wylie Vale, Salk scientist, pioneer and leader, dies at 70" (Press release). Salk Institute. January 6, 2012. Retrieved 2012-01-16.
- 1 2 3 McLellan, Dennis (January 20, 2012), "Wylie W. Vale Jr., who made critical discoveries in brain chemistry, dies" (reprint (Los Angeles Times original)), The Washington Post, washingtonpost.com, retrieved 2012-01-21
- ↑ Wade, Nicholas (January 15, 2012). "Wylie Vale Jr., Groundbreaking Endocrinologist, Dies at 70". The New York Times. Retrieved 2012-01-16.