Tolonidine

Tolonidine
Names
IUPAC name
N-(2-chloro-4-methylphenyl)-4,5-dihydro-1H-imidazol-2-amine
Identifiers
4201-22-3 YesY
Jmol interactive 3D Image
KEGG D07168 YesY
PubChem 72138
UNII I4O795Q03O YesY
Properties
C10H12ClN3
Molar mass 209.67538
Pharmacology
ATC code C01AC04
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Tolonidine is an antihypertensive.[1][2][3]

References

  1. ↑ Cosnier, D.; Duchene-Marullaz, P.; Grimal, J.; Rispat, G.; Streichenberger, G. (1975). "Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (Tolonidine), a new antihypertensive agent. I. Action on blood pressure and heart rate". Arzneimittel-Forschung 25 (10): 1557–1561. PMID 1243037.
  2. ↑ Cosnier, D.; Labrid, C.; Rispat, G.; Streichenberger, G. (1975). "Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. II. Action on cardiac contraction, circulatory parameters, autonomic receptors and diuresis". Arzneimittel-Forschung 25 (11): 1802–1806. PMID 1243090.
  3. ↑ Cosnier, D.; Hache, J.; Labrid, C.; Streichenberger, G. (1975). "Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. III. Action on the secretions of the digestive tract and on the central nervous system, acute toxicity". Arzneimittel-Forschung 25 (12): 1926–1933. PMID 3186.


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