Tilbroquinol

Tilbroquinol
Systematic (IUPAC) name


7-Bromo-5-methylquinolin-8-ol
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	7175-09-9
ATC code	P01AA05
PubChem	CID 65592
ChemSpider	59034
UNII	P6SB125NHA^Y
KEGG	D07351^Y
ChEMBL	CHEMBL1788385
Chemical data
Formula	C₁₀H₈BrNO
Molar mass	238.08 g/mol
SMILES CC1=CC(=C(C2=C1C=CC=N2)O)Br
InChI InChI=1S/C10H8BrNO/c1-6-5-8(11)10(13)9-7(6)3-2-4-12-9/h2-5,13H,1H3 Key:JMOVFFLYGIQXMM-UHFFFAOYSA-N
(verify)

Tilbroquinol is an antiprotozoal agent effective against amoebiasis.^[1] It has also been used against Vibrio cholerae.^[2]

References

↑ International Drug Names
↑ Bougoudogo, F.; Fournier, J. M.; Dodin, A. (1994). "In vitro sensitivity of Vibrio cholerae serotype 0:139 to an intestinal antiseptic tiliquinol-tilbroquinol combination". Bulletin de la Societe de pathologie exotique (1990) 87 (1): 38–40. PMID 8003903.

Antiparasitics – antiprotozoal agents – agents against amoebozoa/amebicide (P01)

Entamoeba

Tissue amebicides

Nitroimidazole derivatives	Metronidazole^# Tinidazole Ornidazole Nimorazole Secnidazole Azanidazole Propenidazole

Other	isoquinoline (Emetine/Dehydroemetine)

Luminal amebicides

Hydroxyquinoline derivatives	Cl (Chlorquinaldol) Br (Tilbroquinol Broxyquinoline) I (Diiodohydroxyquinoline) I, Cl (Clioquinol) related: Chiniofon

Dichloroacetamide derivatives	Diloxanide^# Clefamide Etofamide Teclozan

Aminoglycoside	Paromomycin

Other/ungrouped

Acanthamoeba

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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