Teclozan

Teclozan
Systematic (IUPAC) name

2,2-Dichloro-N-[[4-[[(2,2-dichloroacetyl)-(2-ethoxyethyl)amino]methyl]phenyl]methyl]-N-(2-ethoxyethyl)acetamide
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Number	5560-78-1^Y
ATC code	P01AC04
PubChem	CID 21723
ChemSpider	20418^N
UNII	K9RIF0COUB^Y
KEGG	D06051^Y
Chemical data
Formula	C₂₀H₂₈Cl₄N₂O₄
Molar mass	502.26 g/mol
SMILES CCOCCN(CC1=CC=C(C=C1)CN(CCOCC)C(=O)C(Cl)Cl)C(=O)C(Cl)Cl
InChI InChI=1S/C20H28Cl4N2O4/c1-3-29-11-9-25(19(27)17(21)22)13-15-5-7-16(8-6-15)14-26(10-12-30-4-2)20(28)18(23)24/h5-8,17-18H,3-4,9-14H2,1-2H3^N Key:MSJLJWCAEPENBL-UHFFFAOYSA-N^N
^NY (what is this?) (verify)

Teclozan is an antiprotozoal agent.

It is a dichloroacetamide.^[1]

References

↑ Slighter RG, Yarinsky A, Drobeck HP, Bailey DM (August 1980). "Activity of quinfamide against natural infections of Entamoeba criceti in hamsters: a new potent agent for intestinal amoebiasis". Parasitology 81 (1): 157–68. doi:10.1017/S0031182000055128. PMID 6252530.

Antiparasitics – antiprotozoal agents – agents against amoebozoa/amebicide (P01)

Entamoeba

Tissue amebicides

Nitroimidazole derivatives	Metronidazole^# Tinidazole Ornidazole Nimorazole Secnidazole Azanidazole Propenidazole

Other	isoquinoline (Emetine/Dehydroemetine)

Luminal amebicides

Hydroxyquinoline derivatives	Cl (Chlorquinaldol) Br (Tilbroquinol Broxyquinoline) I (Diiodohydroxyquinoline) I, Cl (Clioquinol) related: Chiniofon

Dichloroacetamide derivatives	Diloxanide^# Clefamide Etofamide Teclozan

Aminoglycoside	Paromomycin

Other/ungrouped

Acanthamoeba

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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