TBC1D1

TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols TBC1D1 ; TBC; TBC1
External IDs OMIM: 609850 MGI: 1889508 HomoloGene: 56856 GeneCards: TBC1D1 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 23216 57915
Ensembl ENSG00000065882 ENSMUSG00000029174
UniProt Q86TI0 Q60949
RefSeq (mRNA) NM_001253912 NM_001289514
RefSeq (protein) NP_001240841 NP_001276443
Location (UCSC) Chr 4:
37.89 – 38.14 Mb
Chr 5:
64.16 – 64.35 Mb
PubMed search

TBC1 domain family member 1 is a protein that in humans is encoded by the TBC1D1 gene.[1][2]

TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6; MIM 604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000).[supplied by OMIM][2]

References

  1. White RA, Pasztor LM, Richardson PM, Zon LI (Sep 2000). "The gene encoding TBC1D1 with homology to the tre-2/USP6 oncogene, BUB2, and cdc16 maps to mouse chromosome 5 and human chromosome 4". Cytogenet Cell Genet 89 (3-4): 272–5. doi:10.1159/000015632. PMID 10965142.
  2. 1 2 "Entrez Gene: TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1".

Further reading


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