Sono-Seq

Sono-Seq (Sonication of Cross-linked Chromatin Sequencing) is a method in molecular biology used for determining the sequences of those DNA regions in the genome near regions of open chromatin of expressed genes. It is also known as "Input" in the Chip-Seq protocol, since it follows the same steps except it doesn't require immunoprecipitation.[1]

References

  1. ↑ Auerbach, R. K.; Euskirchen, G.; Rozowsky, J.; Lamarre-Vincent, N.; Moqtaderi, Z.; Lefrancois, P.; Struhl, K.; Gerstein, M.; Snyder, M. (18 August 2009). "Mapping accessible chromatin regions using Sono-Seq". Proceedings of the National Academy of Sciences 106 (35): 14926–14931. doi:10.1073/pnas.0905443106.
This article is issued from Wikipedia - version of the Saturday, January 03, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.