SIMAP

Similarity Matrix of Proteins, or SIMAP, is a database of protein similarities created using distributed computing, which is freely accessible for scientific purposes. SIMAP uses the FASTA algorithm to precalculate protein similarity, while another application uses hidden Markov models to search for Protein domains.

SIMAP is a joint project of the Technical University of Munich, the Helmholtz Zentrum München, and the University of Vienna.

The project usually got new work units at the beginning of each month. More recently, (2010), inclusion of environmental sequences into the database has required longer periods of activity, several months of continuous work for example. Typically, these updates occurred twice each year.

In the fourth quarter of 2010, the project relocated to the University of Vienna due to the failing electrical infrastructure at the Technical University of Munich. Part of this exercise involved the creation of a project specific URL requiring existing volunteers and users to detach/reattach to the project.

On May 30, 2014, it was announced by project administrators that after a 10-year history, SIMAP would be leaving BOINC by the end of 2014. SIMAP research, however, will go forward with the use of local hardware consisting of "ordinary multi-core CPUs (some hundreds), crunching a SSE-optimized version of the Smith-Waterman algorithm."

Computing platform

SIMAP used the Berkeley Open Infrastructure for Network Computing (BOINC) distributed computing platform.

Application performance notes:

See also

External links


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