SCH-51866

SCH-51866
Names
IUPAC name
(6aR,9aS)-5-Methyl-2-[4-(trifluoromethyl)benzyl]-5,6a,7,8,9,9a-hexahydrocyclopenta[4,5]imidazo[2,1-b]purin-4(3H)-one
Identifiers
ChemSpider 26377910
5270
Jmol interactive 3D Image
PubChem 15473392
Properties
C19H18F3N5O
Molar mass 389.38 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

SCH-51866 is a phosphodiesterase inhibitor.[1][2]

References

  1. "cGMP-phosphodiesterase antagonists inhibit Ca2+-influx in Dictyostelium discoideum and bovine cyclic-nucleotide-gated-channel". Eur. J. Pharmacol. 513 (1-2): 9–20. April 2005. doi:10.1016/j.ejphar.2005.01.047. PMID 15878705.
  2. Beaumont V, Park L, Rassoulpour A, et al. (2014). "The PDE1/5 Inhibitor SCH-51866 Does Not Modify Disease Progression in the R6/2 Mouse Model of Huntington's Disease". PLoS Curr 6. doi:10.1371/currents.hd.3304e87e460b4bb0dc519a29f4deccca. PMC 3923778. PMID 24558637.


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