SBF1

SET binding factor 1

PDB rendering based on 1v5u.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols SBF1 ; CMT4B3; DENND7A; MTMR5
External IDs OMIM: 603560 MGI: 1925230 HomoloGene: 84710 GeneCards: SBF1 Gene
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez 6305 77980
Ensembl ENSG00000100241 ENSMUSG00000036529
UniProt O95248 Q6ZPE2
RefSeq (mRNA) NM_002972 NM_001081030
RefSeq (protein) NP_002963 NP_001074499
Location (UCSC) Chr 22:
50.45 – 50.48 Mb
Chr 15:
89.29 – 89.32 Mb
PubMed search

Myotubularin-related protein 5 is a protein that in humans is encoded by the SBF1 gene.[1][2][3]

Interactions

SBF1 has been shown to interact with MTMR2[4] and SUV39H1.[5]

References

  1. Cui X, De Vivo I, Slany R, Miyamoto A, Firestein R, Cleary ML (April 1998). "Association of SET domain and myotubularin-related proteins modulates growth control". Nat. Genet. 18 (4): 331–7. doi:10.1038/ng0498-331. PMID 9537414.
  2. Laporte J, Blondeau F, Buj-Bello A, Tentler D, Kretz C, Dahl N, Mandel JL (December 1998). "Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human". Hum. Mol. Genet. 7 (11): 1703–12. doi:10.1093/hmg/7.11.1703. PMID 9736772.
  3. "Entrez Gene: SBF1 SET binding factor 1".
  4. Kim SA, Vacratsis PO, Firestein R, Cleary ML, Dixon JE (April 2003). "Regulation of myotubularin-related (MTMR)2 phosphatidylinositol phosphatase by MTMR5, a catalytically inactive phosphatase". Proc. Natl. Acad. Sci. U.S.A. 100 (8): 4492–7. doi:10.1073/pnas.0431052100. PMC 153583. PMID 12668758.
  5. Firestein R, Cui X, Huie P, Cleary ML (July 2000). "Set domain-dependent regulation of transcriptional silencing and growth control by SUV39H1, a mammalian ortholog of Drosophila Su(var)3-9". Mol. Cell. Biol. 20 (13): 4900–9. doi:10.1128/MCB.20.13.4900-4909.2000. PMC 85941. PMID 10848615.

Further reading


This article is issued from Wikipedia - version of the Sunday, August 02, 2015. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.