60S ribosomal protein L41

Ribosomal protein L41
Available structures PDB Human UniProt search: PDBe, RCSB List of PDB id codes 4V6X​, 5AJ0​
Identifiers
Symbols	RPL41 ; L41
External IDs	OMIM: 613315 GeneCards: RPL41 Gene
Gene ontology Molecular function • RNA binding • structural constituent of ribosome Cellular component • cytosol • cytosolic large ribosomal subunit Biological process • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • translation • translational initiation • translational elongation • translational termination • SRP-dependent cotranslational protein targeting to membrane • gene expression • viral process • viral life cycle • viral transcription • cellular protein metabolic process Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6171	n/a
Ensembl	ENSG00000229117	n/a
UniProt	P62945	n/a
RefSeq (mRNA)	NM_001035267	n/a
RefSeq (protein)	NP_001030344	n/a
Location (UCSC)	Chr 12: 56.12 – 56.12 Mb	n/a
PubMed search		n/a

60S ribosomal protein L41 is a protein that in humans is encoded by the RPL41 gene.^[1][2][3]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with the yeast ribosomal protein YL41, belongs to the L41E family of ribosomal proteins. It is located in the cytoplasm. The protein can interact with the beta subunit of protein kinase CKII and can stimulate the phosphorylation of DNA topoisomerase II-alpha by CKII. Two alternative splice variants have been identified, both encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[3]

References

Further reading