RPL18A

Ribosomal protein L18a

Available structures

Ortholog search: PDBe, RCSB

List of PDB id codes
4V6X, 5AJ0

Identifiers

Symbols

RPL18A ; L18A

External IDs

OMIM: 604178 MGI: 1924058 HomoloGene: 68104 GeneCards: RPL18A Gene

Gene ontology
Molecular function	• RNA binding • structural constituent of ribosome • poly(A) RNA binding
Cellular component	• cytosol • membrane • cytosolic large ribosomal subunit
Biological process	• nuclear-transcribed mRNA catabolic process, nonsense-mediated decay • translation • translational initiation • translational elongation • translational termination • SRP-dependent cotranslational protein targeting to membrane • gene expression • viral process • viral life cycle • viral transcription • cellular protein metabolic process
Sources: Amigo / QuickGO

Orthologs

Species

Human

Mouse

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 19:
17.86 – 17.86 Mb

Chr 8:
70.89 – 70.9 Mb

PubMed search

60S ribosomal protein L18a is a protein that in humans is encoded by the RPL18A gene.^[1]^[2]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L18AE family of ribosomal proteins. It is located in the cytoplasm. This gene is co-transcribed with the U68 snoRNA, which is located in its third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.^[2]

References

↑ Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T, Page DC (Aug 1998). "A map of 75 human ribosomal protein genes". Genome Res 8 (5): 509–23. doi:10.1101/gr.8.5.509. PMID 9582194.
1 2 "Entrez Gene: RPL18A ribosomal protein L18a".

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RPL18A

References

Further reading