RNase R

RNase R is an 3'-5' exoribonuclease closely related to RNase II, which has been shown to be involved in selective mRNA degradation, particularly of non stop mRNAs in bacteria.[1][2] RNase R has homologues in many other organisms. When a part of another larger protein has a domain that is very similar to RNase R, this is called an RNase R domain.

References

  1. ↑ Cheng; Deutscher, MP; et al. (2005). "An important role for RNase R in mRNA decay". Molecular Cell 17 (2): 313–8. doi:10.1016/j.molcel.2004.11.048. PMID 15664199.
  2. ↑ Venkataraman, K; Guja, KE; Garcia-Diaz, M; Karzai, AW (2014). "Non-stop mRNA decay: a special attribute of trans-translation mediated ribosome rescue.". Frontiers in Microbiology 5: 93. doi:10.3389/fmicb.2014.00093. PMC 3949413. PMID 24653719.


This article is issued from Wikipedia - version of the Friday, February 05, 2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.