RNase D

Ribonuclease D
Structure of the RNase D protein
Identifiers
Symbol	RNASED
Other data
EC number	3.1.13.5

RNase D is one of the seven exoribonucleases identified in E. coli. It is a 3'-5' exoribonuclease which has been shown to be involved in the 3' processing of various stable RNA molecules.^[1] It is known to add the 3' CCA sequence to tRNA in prokaryotic tRNA processing. RNase D has homologues in many other organisms. When a part of another larger protein has a domain that is very similar to RNase D, this is called an RNase D domain.

References

↑ Zuo; Wang, Y; Malhotra, A; et al. (2005). "Crystal structure of Escherichia coli RNase D, an exoribonuclease involved in structured RNA processing". Structure 13 (7): 973–84. doi:10.1016/j.str.2005.04.015. PMID 16004870.

External links

Crystal structure of E. coli RNase D at the RCSB Protein Data Bank

Hydrolase: esterases (EC 3.1)

3.1.1: Carboxylic
ester hydrolases

Lipase

Phospholipase
- A1
- A2
- B

3.1.2: Thioesterase

3.1.3: Phosphatase

3.1.4: Phosphodiesterase

3.1.6: Sulfatase

Nuclease (includes
deoxyribonuclease and
ribonuclease)

3.1.11-16: Exonuclease

Exodeoxyribonuclease	RecBCD

Exoribonuclease	Oligonucleotidase

3.1.21-31: Endonuclease

Endodeoxyribonuclease	Deoxyribonuclease I Deoxyribonuclease II Deoxyribonuclease IV Restriction enzyme UvrABC endonuclease

Endoribonuclease	RNase III RNase H 1 2A 2B 2C RNase P RNase A 1 2 3 4/5 RNase T1 RNA-induced silencing complex

either deoxy- or ribo-	Aspergillus nuclease S1 Micrococcal nuclease

Proteins: enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases(list) EC2 Transferases(list) EC3 Hydrolases(list) EC4 Lyases(list) EC5 Isomerases(list) EC6 Ligases(list)

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