RAB14

RAB14, member RAS oncogene family

PDB rendering based on 1z0f.

Available structures

Ortholog search: PDBe, RCSB

List of PDB id codes
1Z0F, 4D0G, 4DRZ

Identifiers

Symbols

RAB14 ; FBP; RAB-14

External IDs

OMIM: 612673 MGI: 1915615 HomoloGene: 48679 GeneCards: RAB14 Gene

Gene ontology
Molecular function	• glycoprotein binding • GTPase activity • protein binding • GTP binding • GDP binding • myosin V binding
Cellular component	• Golgi membrane • intracellular • lysosome • lysosomal membrane • early endosome • late endosome • rough endoplasmic reticulum • Golgi stack • trans-Golgi network • cytosol • plasma membrane • apical plasma membrane • trans-Golgi network transport vesicle • cytoplasmic vesicle membrane • phagocytic vesicle membrane • early endosome membrane • nuclear outer membrane-endoplasmic reticulum membrane network • intracellular membrane-bounded organelle • phagocytic vesicle • perinuclear region of cytoplasm • recycling endosome • extracellular exosome • primary cilium • alveolar lamellar body
Biological process	• intracellular protein transport • Golgi to endosome transport • body fluid secretion • metabolic process • fibroblast growth factor receptor signaling pathway • embryo development • vesicle-mediated transport • endocytic recycling • Rab protein signal transduction • regulation of protein localization • defense response to bacterium • apical protein localization • intracellular transport • membrane organization • phagolysosome assembly involved in apoptotic cell clearance
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 9:
121.18 – 121.22 Mb

Chr 2:
35.18 – 35.2 Mb

PubMed search

Ras-related protein Rab-14 is a protein that in humans is encoded by the RAB14 gene.^[1]^[2]^[3]

References

↑ de Leeuw HP, Koster PM, Calafat J, Janssen H, van Zonneveld AJ, van Mourik JA, Voorberg J (Dec 1998). "Small GTP-binding proteins in human endothelial cells". Br J Haematol 103 (1): 15–9. doi:10.1046/j.1365-2141.1998.00965.x. PMID 9792283.
↑ Junutula JR, De Maziere AM, Peden AA, Ervin KE, Advani RJ, van Dijk SM, Klumperman J, Scheller RH (Apr 2004). "Rab14 is involved in membrane trafficking between the Golgi complex and endosomes". Mol Biol Cell 15 (5): 2218–29. doi:10.1091/mbc.E03-10-0777. PMC 404017. PMID 15004230.
↑ "Entrez Gene: RAB14 RAB14, member RAS oncogene family".

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PDB gallery

1z0f: GDP-Bound Rab14 GTPase

2aed: Crystal structure of human RAB14

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RAB14

References

Further reading